A convenient solvent-specific synthesis of 4-[4-acetoxy-3-(3-methylbut-2- enyl)phenyl]butyric acid

Majekodunmi O. Fatope*, Joseph I. Okogun

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةمراجعة النظراء

9 اقتباسات (Scopus)

ملخص

Three types of reaction, esterification, C-alkenylation, and O-alkenylation, have been observed between the di-anion (4) and 1-bromo-3-methylbut-2-ene (5) in different solvent systems. Our studies of the effect of the medium on the behaviour of the di-anion (4) towards electrophilic attack by the bromo-alkene (5) resulted in the synthesis of analogues (2) and (6d) of a known anti-sickling agent (3) in high yield. The regioselectivity of the alkenylation reactions is rationalised in terms of solvent polarity.

اللغة الأصليةEnglish
الصفحات (من إلى)1601-1603
عدد الصفحات3
دوريةJournal of the Chemical Society, Perkin Transactions 1
المعرِّفات الرقمية للأشياء
حالة النشرPublished - 1982
منشور خارجيًانعم

ASJC Scopus subject areas

  • ???subjectarea.asjc.1600???

بصمة

أدرس بدقة موضوعات البحث “A convenient solvent-specific synthesis of 4-[4-acetoxy-3-(3-methylbut-2- enyl)phenyl]butyric acid'. فهما يشكلان معًا بصمة فريدة.

قم بذكر هذا