Worldwide Network for Blood and Marrow Transplantation Recommendations for Establishing a Hematopoietic Stem Cell Transplantation Program in Countries with Limited Resources, Part II: Clinical, Technical, and Socioeconomic Considerations

Mahmoud Aljurf*, Daniel Weisdorf, Shahrukh Hashmi, Amr Nassar, Eliane Gluckman, Mohamad Mohty, Doug Rizzo, Marcelo Pasquini, Mehdi Hamadani, Wael Saber, Parameswaran Hari, Mohamed Kharfan-Dabaja, Navneet Majhail, Usama Gerges, Amir Ali Hamidieh, Fazal Hussain, Alaa Elhaddad, Hossam K. Mahmoud, Abdelghani Tbakhi, Tarek Ben OthmanRose Marie Hamladji, Mohamed Amine Bekadja, Parvez Ahmed, Ali Bazarbachi, Salman Adil, Salman Alkindi, Saleh Ladeb, David Dennison, Moosa Patel, Peihua Lu, Asma El Quessar, Shinichiro Okamoto, Yoshiko Atsuta, Ayman Alhejazi, Mouhab F. Ayas, Syed O. Ahmed, Nickolas Novitzky, Alok Srivastava, Adriana Seber, Hassan El Solh, Ardeshir Ghavamzadeh, Dennis Confer, Yoshihisa Kodera, Greinix Hildegard, Jeff Szer, Mary M. Horowitz, Dietger Niederwieser

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

9 Citations (Scopus)


The development of hematopoietic stem cell transplantation (HSCT) programs can face significant challenges in most developing countries because such endeavors must compete with other government health care priorities, including the delivery of basic services. Although this is may be a limiting factor, these countries should prioritize development of the needed expertise to offer state-of-the-art treatments, including transplantation, by providing financial, technological, legal, ethical, and other needed support. This would prove beneficial in providing successful programs customized to the needs of their population and potentially provide long-term cost savings by circumventing the need for their citizens to seek care abroad. The costs of establishing an HSCT program and the costs of the HSCT procedure itself can be substantial barriers in developing countries. In addition, socioeconomic factors intrinsic to specific countries can influence access to HSCT, patient eligibility for HSCT, and timely utilization of HSCT center capabilities. This report describes recommendations from the Worldwide Network for Blood and Marrow Transplantation for establishing HSCT programs, with a specific focus on developing countries, and identifies challenges and opportunities for providing this specialized procedure in resource-constrained settings.

Original languageEnglish
JournalBiology of Blood and Marrow Transplantation
Publication statusAccepted/In press - 2019
Externally publishedYes


  • Bone marrow transplantation
  • Developing countries
  • Low-income countries

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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