TY - JOUR
T1 - West Nile virus positive blood donation and subsequent entomological investigation, Austria, 2014
AU - Kolodziejek, Jolanta
AU - Seidel, Bernhard
AU - Jungbauer, Christof
AU - Dimmel, Katharina
AU - Kolodziejek, Michael
AU - Rudolf, Ivo
AU - Hubálek, Zdenek
AU - Allerberger, Franz
AU - Nowotny, Norbert
N1 - Publisher Copyright:
© 2015 Kolodziejek et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2015/5/11
Y1 - 2015/5/11
N2 - The detection of West Nile virus (WNV) nucleic acid in a blood donation from Vienna, Austria, as well as in Culex pipiens pupae and egg rafts, sampled close to the donor's residence, is reported. Complete genomic sequences of the human- and mosquito-derived viruses were established, genetically compared and phylogenetically analyzed. The viruses were not identical, but closely related to each other and to recent Czech and Italian isolates, indicating co-circulation of related WNV strains within a confined geographic area. The detection of WNV in a blood donation originating from an area with low WNV prevalence in humans (only three serologically diagnosed cases between 2008 and 2014) is surprising and emphasizes the importance of WNV nucleic acid testing of blood donations even in such areas, along with active mosquito surveillance programs.
AB - The detection of West Nile virus (WNV) nucleic acid in a blood donation from Vienna, Austria, as well as in Culex pipiens pupae and egg rafts, sampled close to the donor's residence, is reported. Complete genomic sequences of the human- and mosquito-derived viruses were established, genetically compared and phylogenetically analyzed. The viruses were not identical, but closely related to each other and to recent Czech and Italian isolates, indicating co-circulation of related WNV strains within a confined geographic area. The detection of WNV in a blood donation originating from an area with low WNV prevalence in humans (only three serologically diagnosed cases between 2008 and 2014) is surprising and emphasizes the importance of WNV nucleic acid testing of blood donations even in such areas, along with active mosquito surveillance programs.
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U2 - 10.1371/journal.pone.0126381
DO - 10.1371/journal.pone.0126381
M3 - Article
C2 - 25961567
AN - SCOPUS:84930652234
SN - 1932-6203
VL - 10
JO - PLoS One
JF - PLoS One
IS - 5
M1 - e0126381
ER -