Deficiência de vitamina b12 em cabritos recém-desmamados associada à infecção clínica por eimeria arloingi

Translated title of the contribution: Vitamin b12 deficiency in newly weaned goat kids associated with clinical infection with eimeria arloingi

Khalid Al-Habsi, Haytham Ali*, Kaadhia Al-Kharousi, Elshafie Ibrahim Elshafie, Rashid Al-Busaidi, Anwar Muhiuddin, Eugene Harper Johnson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A severe outbreak of diarrhea associated with poor growth was reported in ten newly weaned goat kids that originated from a research farm (Group A). Two of these kids underwent necropsy examination. Five goat kids of the same age maintained in the same pen showed no clinical signs (Group B). The clinical, gross pathological and histopathological features of the clinically sick animals were consistent with severe coccidiosis. Group A animals had significantly lower levels of serum vitamin B12 (<200 pg/ml) compared with group B animals (2000 pg/ml). In addition, kids belonging to group A had significantly higher Eimeria arloingi oocysts per gram (OPG) of faeces (101,400/g) compared with kids of group B (9,154/g). Microscopy and molecular tools (18S rRNA and COI genes) confirmed that the goat kids were infected with the caprine protozoan parasite E. arloingi. This study provides a definitive association between low levels of serum vitamin B12 and clinical E. arloingi infection, and also provides support to our previous studies that demonstrated how low levels of serum vitamin B12 leads to an impairment of neutrophil function and thereby potential lowered immunity to pathogens.

Translated title of the contributionVitamin b12 deficiency in newly weaned goat kids associated with clinical infection with eimeria arloingi
Original languagePortuguese
Article numbere005920
Pages (from-to)1-9
Number of pages9
JournalRevista Brasileira de Parasitologia Veterinaria
Volume29
Issue number4
DOIs
Publication statusPublished - Jan 1 2020

Keywords

  • 18S rRNA
  • Cobalt
  • COI
  • Eimeria arloingi
  • Goats
  • Vitamin B

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)

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