VIPoma crisis: Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide

Omayma ElShafie, Christopher Grant, Aisha Al-Hamdani, Rajeev Jain, Nicholas Woodhouse

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report the case of a 57-year-old male physician who presented with a life threatening secretory and refractory diarrhoea of around 20 L/day. This was complicated by severe hypotension, hypokalaemia, hypercalcaemia, renal failure requiring dialysis, metabolic acidosis, cardiorespiratory arrest and ventilation for 12 days. His diarrhoea responded immediately to the first dose of a therapeutic trial of subcutaneous octreotide 100 mcg 8 hourly which was started on clinical grounds alone before any investigations were carried out. After one day he was extubated and his blood pressure returned to normal. When a functioning neuroendocrine tumour is suspected clinically, the use of octreotide can, as in this case, be life saving.

Original languageEnglish
Pages (from-to)104-108
Number of pages5
JournalSultan Qaboos University Medical Journal
Volume11
Issue number1
Publication statusPublished - Feb 2011

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Keywords

  • Cardiopulmonary arrest
  • Case report
  • Chromogranin A
  • Diarrhoea
  • Neuroendocrine tumour
  • Octreotide
  • Oman
  • Pancreatic tumour
  • VIPoma

ASJC Scopus subject areas

  • Medicine(all)

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