Validation of the GRACE risk score for hospital mortality in patients with acute coronary syndrome in the Arab Middle East

Afzalhussein Yusufali, Mohammad Zubaid, Ibrahim Al-Zakwani, Alawi A. Alsheikh-Ali, Mouaz H. Al-Mallah, Jassim Al Suwaidi, Wael Almahmeed, Wafa Rashed, Kadhim Sulaiman, Haitham Amin

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Our objective was to validate the Global Registry of Acute Coronary Events (GRACE) risk score for in-hospital mortality in a Middle Eastern acute coronary syndrome (ACS) population enrolled in the Gulf Registry of Acute Coronary Events (Gulf RACE). Out of 8176, unselected, consecutive patients with ACS, during 6 months in 2006 and 2007 from 63 hospitals in 6 Arab countries in the Middle East Gulf region, 7709 (94.3%) with available data were included. The main outcome measures were discriminatory performance (using C-index) and calibration of the GRACE risk score (in-hospital mortality predicted by GRACE risk score versus the actual mortality). In-hospital mortality in the Gulf RACE was 3.09% (n = 238). The discriminatory performance of the GRACE risk scores in the Gulf RACE was good overall (C-index = 0.86). Observed and predicted risk corresponded well in each stratum of risk of in-hospital mortality. This suggests its suitability for clinical use in this patient population.

Original languageEnglish
Pages (from-to)390-396
Number of pages7
JournalAngiology
Volume62
Issue number5
DOIs
Publication statusPublished - Jul 2011

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Middle East
Acute Coronary Syndrome
Hospital Mortality
Registries
Calibration
Population
Outcome Assessment (Health Care)
Mortality

Keywords

  • acute coronary syndrome
  • prognosis
  • risk scores
  • risk stratification

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Validation of the GRACE risk score for hospital mortality in patients with acute coronary syndrome in the Arab Middle East. / Yusufali, Afzalhussein; Zubaid, Mohammad; Al-Zakwani, Ibrahim; Alsheikh-Ali, Alawi A.; Al-Mallah, Mouaz H.; Al Suwaidi, Jassim; Almahmeed, Wael; Rashed, Wafa; Sulaiman, Kadhim; Amin, Haitham.

In: Angiology, Vol. 62, No. 5, 07.2011, p. 390-396.

Research output: Contribution to journalArticle

Yusufali, A, Zubaid, M, Al-Zakwani, I, Alsheikh-Ali, AA, Al-Mallah, MH, Al Suwaidi, J, Almahmeed, W, Rashed, W, Sulaiman, K & Amin, H 2011, 'Validation of the GRACE risk score for hospital mortality in patients with acute coronary syndrome in the Arab Middle East', Angiology, vol. 62, no. 5, pp. 390-396. https://doi.org/10.1177/0003319710387921
Yusufali, Afzalhussein ; Zubaid, Mohammad ; Al-Zakwani, Ibrahim ; Alsheikh-Ali, Alawi A. ; Al-Mallah, Mouaz H. ; Al Suwaidi, Jassim ; Almahmeed, Wael ; Rashed, Wafa ; Sulaiman, Kadhim ; Amin, Haitham. / Validation of the GRACE risk score for hospital mortality in patients with acute coronary syndrome in the Arab Middle East. In: Angiology. 2011 ; Vol. 62, No. 5. pp. 390-396.
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