TY - JOUR
T1 - Validation of the GRACE risk score for hospital mortality in patients with acute coronary syndrome in the Arab Middle East
AU - Yusufali, Afzalhussein
AU - Zubaid, Mohammad
AU - Al-Zakwani, Ibrahim
AU - Alsheikh-Ali, Alawi A.
AU - Al-Mallah, Mouaz H.
AU - Al Suwaidi, Jassim
AU - Almahmeed, Wael
AU - Rashed, Wafa
AU - Sulaiman, Kadhim
AU - Amin, Haitham
PY - 2011/7
Y1 - 2011/7
N2 - Our objective was to validate the Global Registry of Acute Coronary Events (GRACE) risk score for in-hospital mortality in a Middle Eastern acute coronary syndrome (ACS) population enrolled in the Gulf Registry of Acute Coronary Events (Gulf RACE). Out of 8176, unselected, consecutive patients with ACS, during 6 months in 2006 and 2007 from 63 hospitals in 6 Arab countries in the Middle East Gulf region, 7709 (94.3%) with available data were included. The main outcome measures were discriminatory performance (using C-index) and calibration of the GRACE risk score (in-hospital mortality predicted by GRACE risk score versus the actual mortality). In-hospital mortality in the Gulf RACE was 3.09% (n = 238). The discriminatory performance of the GRACE risk scores in the Gulf RACE was good overall (C-index = 0.86). Observed and predicted risk corresponded well in each stratum of risk of in-hospital mortality. This suggests its suitability for clinical use in this patient population.
AB - Our objective was to validate the Global Registry of Acute Coronary Events (GRACE) risk score for in-hospital mortality in a Middle Eastern acute coronary syndrome (ACS) population enrolled in the Gulf Registry of Acute Coronary Events (Gulf RACE). Out of 8176, unselected, consecutive patients with ACS, during 6 months in 2006 and 2007 from 63 hospitals in 6 Arab countries in the Middle East Gulf region, 7709 (94.3%) with available data were included. The main outcome measures were discriminatory performance (using C-index) and calibration of the GRACE risk score (in-hospital mortality predicted by GRACE risk score versus the actual mortality). In-hospital mortality in the Gulf RACE was 3.09% (n = 238). The discriminatory performance of the GRACE risk scores in the Gulf RACE was good overall (C-index = 0.86). Observed and predicted risk corresponded well in each stratum of risk of in-hospital mortality. This suggests its suitability for clinical use in this patient population.
KW - acute coronary syndrome
KW - prognosis
KW - risk scores
KW - risk stratification
UR - http://www.scopus.com/inward/record.url?scp=79957527583&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79957527583&partnerID=8YFLogxK
U2 - 10.1177/0003319710387921
DO - 10.1177/0003319710387921
M3 - Article
C2 - 21307002
AN - SCOPUS:79957527583
SN - 0003-3197
VL - 62
SP - 390
EP - 396
JO - Angiology
JF - Angiology
IS - 5
ER -