Vaccination of calves against Salmonella dublin with aromatic-dependent Salmonella typhimurium.

B. P. Smith, M. Reina-Guerra, B. A. Stocker, S. K. Hoiseth, E. H. Johnson

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Ten Holstein calves were divided into 2 groups. Five calves served as nonvaccinated controls, and 5 calves were vaccinated IM at 2 and 3 weeks of age with 10(9) aromatic-dependent (aro-) Salmonella typhimurium strain SL1479 containing O antigens 1, 4, 12. Serious adverse reactions to vaccination were not observed in the calves. Mean maximum rectal temperature increase in the vaccinated calves was 1.5 C. One calf had diarrhea and depressed appetite for 1 day after vaccination. At 5 weeks of age, all calves were challenge exposed orally with 1.5 X 10(11) virulent S dublin strain SL1367 (O antigens 9,12). After challenge-exposure inoculum was given, 1 of 5 vaccinated calves died and 4 of the 5 nonvaccinated calves died (P less than 0.05). Thus, some cross serotype protection against S dublin was induced by parenteral vaccination of calves with aro- S typhimurium strain SL1479, although protection was not complete.

Original languageEnglish
Pages (from-to)1858-1861
Number of pages4
JournalAmerican Journal of Veterinary Research
Volume45
Issue number9
Publication statusPublished - Sep 1984

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Salmonella Dublin
Salmonella typhimurium
Salmonella Typhimurium
Salmonella
aromatic compounds
O Antigens
Vaccination
vaccination
calves
Cross Protection
Appetite
Diarrhea
Temperature
antigens
appetite
diarrhea
inoculum
serotypes
Holstein

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Vaccination of calves against Salmonella dublin with aromatic-dependent Salmonella typhimurium. / Smith, B. P.; Reina-Guerra, M.; Stocker, B. A.; Hoiseth, S. K.; Johnson, E. H.

In: American Journal of Veterinary Research, Vol. 45, No. 9, 09.1984, p. 1858-1861.

Research output: Contribution to journalArticle

Smith, B. P. ; Reina-Guerra, M. ; Stocker, B. A. ; Hoiseth, S. K. ; Johnson, E. H. / Vaccination of calves against Salmonella dublin with aromatic-dependent Salmonella typhimurium. In: American Journal of Veterinary Research. 1984 ; Vol. 45, No. 9. pp. 1858-1861.
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