TY - JOUR
T1 - Urinary stone composition in Oman
T2 - with high incidence of cystinuria
AU - Al-Marhoon, Mohammed S.
AU - Bayoumi, Riad
AU - Al-Farsi, Yahya
AU - Al-Hinai, Abdullhakeem
AU - Al-Maskary, Sultan
AU - Venkiteswaran, Krishna
AU - Al-Busaidi, Qassim
AU - Mathew, Josephkunju
AU - Rhman, Khalid
AU - Sharif, Omar
AU - Aquil, Shahid
AU - Al-Hashmi, Intisar
N1 - Funding Information:
My thanks to all clinical staff, nurses and research assistants for their support in this research. This work has been financially supported by the Oman Research Council (TRC). The laboratory space and administrative matters have been supported by Sultan Qaboos University.
Publisher Copyright:
© 2015, Springer-Verlag Berlin Heidelberg.
PY - 2015/6/22
Y1 - 2015/6/22
N2 - Urinary stones are a common problem in Oman and their composition is unknown. The aim of this study is to analyze the components of urinary stones of Omani patients and use the obtained data for future studies of etiology, treatment, and prevention. Urinary stones of 255 consecutive patients were collected at the Sultan Qaboos University Hospital. Stones were analyzed by Fourier transform infrared spectrophotometer. The biochemical, metabolic, and radiological data relating to the patients and stones were collected. The mean age was 41 years, with M:F ratio of 3.7:1. The common comorbidities associated with stone formation were hypertension; diabetes, benign prostate hyperplasia; urinary tract infection; obesity; and atrophic kidney. The common presentation was renal colic and flank pain (96 %). Stones were surgically retrieved in 70 % of patients. Mean stone size was 9 ± 0.5 mm (range 1.3–80). Stone formers had a BMI ≥ 25 in 56 % (P = 0.006) and positive family history of stones in 3.8 %. The most common stones in Oman were as follows: Calcium Oxalates 45 % (114/255); Mixed calcium phosphates & calcium oxalates 22 % (55/255); Uric Acid 16 % (40/255); and Cystine 4 % (10/255). The most common urinary stones in Oman are Calcium Oxalates. Overweight is an important risk factor associated with stone formation. The hereditary Cystine stones are three times more common in Oman than what is reported in the literature that needs further genetic studies.
AB - Urinary stones are a common problem in Oman and their composition is unknown. The aim of this study is to analyze the components of urinary stones of Omani patients and use the obtained data for future studies of etiology, treatment, and prevention. Urinary stones of 255 consecutive patients were collected at the Sultan Qaboos University Hospital. Stones were analyzed by Fourier transform infrared spectrophotometer. The biochemical, metabolic, and radiological data relating to the patients and stones were collected. The mean age was 41 years, with M:F ratio of 3.7:1. The common comorbidities associated with stone formation were hypertension; diabetes, benign prostate hyperplasia; urinary tract infection; obesity; and atrophic kidney. The common presentation was renal colic and flank pain (96 %). Stones were surgically retrieved in 70 % of patients. Mean stone size was 9 ± 0.5 mm (range 1.3–80). Stone formers had a BMI ≥ 25 in 56 % (P = 0.006) and positive family history of stones in 3.8 %. The most common stones in Oman were as follows: Calcium Oxalates 45 % (114/255); Mixed calcium phosphates & calcium oxalates 22 % (55/255); Uric Acid 16 % (40/255); and Cystine 4 % (10/255). The most common urinary stones in Oman are Calcium Oxalates. Overweight is an important risk factor associated with stone formation. The hereditary Cystine stones are three times more common in Oman than what is reported in the literature that needs further genetic studies.
KW - Analysis
KW - Cystine
KW - Oman
KW - Stones
KW - Urinary
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U2 - 10.1007/s00240-015-0763-7
DO - 10.1007/s00240-015-0763-7
M3 - Article
C2 - 25805105
AN - SCOPUS:84940000959
SN - 2194-7228
VL - 43
SP - 207
EP - 211
JO - Urolithiasis
JF - Urolithiasis
IS - 3
M1 - 2
ER -