Unilateral Proptosis: A Rare Presenting Sign of Acute Myeloid Leukemia

Abdullah Al-Mujaini; Majid Al-Shaaibi; Tahani Al-Mughaizwi; Yasser Wali; Anuradha Ganesh

doi:10.5001/omj.2022.10

Unilateral Proptosis: A Rare Presenting Sign of Acute Myeloid Leukemia

Abdullah Al-Mujaini, Majid Al-Shaaibi, Tahani Al-Mughaizwi, Yasser Wali^*, Anuradha Ganesh

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Unilateral proptosis is a rare initial presenting sign of acute myeloid leukemia (AML). We report a case of unilateral proptosis in a six-year-old girl as the initial manifestation of AML. The cancer link was initially missed and the case was investigated as one of hyperthyroidism. Peripheral blood smear and bone marrow aspirate evaluation showed signs diagnostic of AML. Computed tomography scan of orbits showed infiltrative process in the right orbit, right maxillary, and right ethmoidal sinuses. Unilateral proptosis as an extramedullary first presenting feature of AML is very rare; however, it should always be considered in the differential diagnosis of proptosis in pediatric age group.

Original language	English
Article number	e400
Pages (from-to)	e400
Journal	Oman Medical Journal
Volume	37
Issue number	4
DOIs	https://doi.org/10.5001/omj.2022.10
Publication status	Published - Jul 2022

Keywords

Acute Myeloid Leukemia
Oman
Orbit
Pediatric
Proptosis

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.5001/omj.2022.10

Cite this

@article{51e5545c5ed640dd997a9446c0b5954b,

title = "Unilateral Proptosis: A Rare Presenting Sign of Acute Myeloid Leukemia",

abstract = "Unilateral proptosis is a rare initial presenting sign of acute myeloid leukemia (AML). We report a case of unilateral proptosis in a six-year-old girl as the initial manifestation of AML. The cancer link was initially missed and the case was investigated as one of hyperthyroidism. Peripheral blood smear and bone marrow aspirate evaluation showed signs diagnostic of AML. Computed tomography scan of orbits showed infiltrative process in the right orbit, right maxillary, and right ethmoidal sinuses. Unilateral proptosis as an extramedullary first presenting feature of AML is very rare; however, it should always be considered in the differential diagnosis of proptosis in pediatric age group.",

keywords = "Acute Myeloid Leukemia, Oman, Orbit, Pediatric, Proptosis",

author = "Abdullah Al-Mujaini and Majid Al-Shaaibi and Tahani Al-Mughaizwi and Yasser Wali and Anuradha Ganesh",

note = "The OMJ is Published Bimonthly and Copyrighted 2022 by the OMSB.",

year = "2022",

month = jul,

doi = "10.5001/omj.2022.10",

language = "English",

volume = "37",

pages = "e400",

journal = "Oman Medical Journal",

issn = "1999-768X",

publisher = "Oman Medical Specialty Board",

number = "4",

}

TY - JOUR

T1 - Unilateral Proptosis

T2 - A Rare Presenting Sign of Acute Myeloid Leukemia

AU - Al-Mujaini, Abdullah

AU - Al-Shaaibi, Majid

AU - Al-Mughaizwi, Tahani

AU - Wali, Yasser

AU - Ganesh, Anuradha

N1 - The OMJ is Published Bimonthly and Copyrighted 2022 by the OMSB.

PY - 2022/7

Y1 - 2022/7

N2 - Unilateral proptosis is a rare initial presenting sign of acute myeloid leukemia (AML). We report a case of unilateral proptosis in a six-year-old girl as the initial manifestation of AML. The cancer link was initially missed and the case was investigated as one of hyperthyroidism. Peripheral blood smear and bone marrow aspirate evaluation showed signs diagnostic of AML. Computed tomography scan of orbits showed infiltrative process in the right orbit, right maxillary, and right ethmoidal sinuses. Unilateral proptosis as an extramedullary first presenting feature of AML is very rare; however, it should always be considered in the differential diagnosis of proptosis in pediatric age group.

AB - Unilateral proptosis is a rare initial presenting sign of acute myeloid leukemia (AML). We report a case of unilateral proptosis in a six-year-old girl as the initial manifestation of AML. The cancer link was initially missed and the case was investigated as one of hyperthyroidism. Peripheral blood smear and bone marrow aspirate evaluation showed signs diagnostic of AML. Computed tomography scan of orbits showed infiltrative process in the right orbit, right maxillary, and right ethmoidal sinuses. Unilateral proptosis as an extramedullary first presenting feature of AML is very rare; however, it should always be considered in the differential diagnosis of proptosis in pediatric age group.

KW - Acute Myeloid Leukemia

KW - Oman

KW - Orbit

KW - Pediatric

KW - Proptosis

UR - http://www.scopus.com/inward/record.url?scp=85133938788&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85133938788&partnerID=8YFLogxK

U2 - 10.5001/omj.2022.10

DO - 10.5001/omj.2022.10

M3 - Article

C2 - 35915765

AN - SCOPUS:85133938788

SN - 1999-768X

VL - 37

SP - e400

JO - Oman Medical Journal

JF - Oman Medical Journal

IS - 4

M1 - e400

ER -

Unilateral Proptosis: A Rare Presenting Sign of Acute Myeloid Leukemia

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this