Transthoracic electrical bioimpedence cardiac output

Comparison with multigated equillibrium radionuclide cardiography

Arunodaya R. Gujjar, K. Muralidhar, Abhijit Bhandopadhyaya, T. N. Sathyaprabha, P. Janaki, B. K. Mahalla, Ratan Gupta, Sanjay Banakal, P. S. Jairaj

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Introduction: Thoracic electrical bioimpedance (TEB) for measuring cardiac output (CO) is being explored increasingly as an alternative to pulmonary artery catheter. The major advantage of this technology is that it is non-invasive and easy to perform. Several studies have compared it to thermodilution cardiac output using PA catheter, with variable correlation. Multigated radionuclide equilibrium cardiography (RNEC) method of cardiac output measurement is known to be reliable. Objective: To compare cardiac output measured by thoracic electrical bioimpdenace with that measured by multigated radionuclide equilibrium cardiography. Patients and methods: CO studies were performed sequentially at a single sitting by TEB and RNEC methods among patients with cardiac symptoms referred for radionuclide study as part of their evaluation. TEB CO was measured by placing two pairs of electrodes on either side of neck and two other pairs on either side of the lower chest. Stroke volume was estimated from the sequential changes in transthoracic electrical bioimpedance induced by rhythmic aortic blood flow, using Kubicek equation. RNEC-CO was measured by intravenous injection of radio-active Technitiumtagged RBCs followed by ECG gated blood pool imaging over the chest (MUGA study). Bland-Altman analysis was used to compare the measurements. Results: A total of 32 subjects with proven or suspected ischemic heart disease, but without overt cardiac failure, edema or arrhythmias were studied (M:F::26:6; mean age: 48 ± 12 years). The mean TEB-CO was 3.54 ± 1.052 l/min and mean RNEC-CO was 3.907 ± 0.952 l/min. Correlation coefficient (r) for these measurements was 0.67 (p <0.01), with bias: -0.421 l/min; precision: 1.557 l/min; and percentage error of measurement: 42.35%. Conclusions: This study observed a moderate correlation between TEB and RNEC methods of CO measurement. Further studies are indicated to explore the relative utility of TEB in comparison with RNEC as well as other methods of CO measurement before considering its use in patients with ischemic heart disease.

Original languageEnglish
Pages (from-to)155-159
Number of pages5
JournalJournal of Clinical Monitoring and Computing
Volume24
Issue number2
DOIs
Publication statusPublished - Apr 2010

Fingerprint

Radioisotopes
Cardiac Output
Thorax
Myocardial Ischemia
Cardiac Edema
Catheters
Gated Blood-Pool Imaging
Thermodilution
Radio
Intravenous Injections
Stroke Volume
Pulmonary Artery
Cardiac Arrhythmias
Electrocardiography
Electrodes
Neck
Heart Failure
Technology

Keywords

  • Cardiac output
  • MUGA
  • Multigated equilibrium radionuclide cardiography
  • Thoracic electrical bioimpedance

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Critical Care and Intensive Care Medicine
  • Health Informatics

Cite this

Transthoracic electrical bioimpedence cardiac output : Comparison with multigated equillibrium radionuclide cardiography. / Gujjar, Arunodaya R.; Muralidhar, K.; Bhandopadhyaya, Abhijit; Sathyaprabha, T. N.; Janaki, P.; Mahalla, B. K.; Gupta, Ratan; Banakal, Sanjay; Jairaj, P. S.

In: Journal of Clinical Monitoring and Computing, Vol. 24, No. 2, 04.2010, p. 155-159.

Research output: Contribution to journalArticle

Gujjar, AR, Muralidhar, K, Bhandopadhyaya, A, Sathyaprabha, TN, Janaki, P, Mahalla, BK, Gupta, R, Banakal, S & Jairaj, PS 2010, 'Transthoracic electrical bioimpedence cardiac output: Comparison with multigated equillibrium radionuclide cardiography', Journal of Clinical Monitoring and Computing, vol. 24, no. 2, pp. 155-159. https://doi.org/10.1007/s10877-010-9225-5
Gujjar, Arunodaya R. ; Muralidhar, K. ; Bhandopadhyaya, Abhijit ; Sathyaprabha, T. N. ; Janaki, P. ; Mahalla, B. K. ; Gupta, Ratan ; Banakal, Sanjay ; Jairaj, P. S. / Transthoracic electrical bioimpedence cardiac output : Comparison with multigated equillibrium radionuclide cardiography. In: Journal of Clinical Monitoring and Computing. 2010 ; Vol. 24, No. 2. pp. 155-159.
@article{b8d549f7bcd74682acc23cb803e81ded,
title = "Transthoracic electrical bioimpedence cardiac output: Comparison with multigated equillibrium radionuclide cardiography",
abstract = "Introduction: Thoracic electrical bioimpedance (TEB) for measuring cardiac output (CO) is being explored increasingly as an alternative to pulmonary artery catheter. The major advantage of this technology is that it is non-invasive and easy to perform. Several studies have compared it to thermodilution cardiac output using PA catheter, with variable correlation. Multigated radionuclide equilibrium cardiography (RNEC) method of cardiac output measurement is known to be reliable. Objective: To compare cardiac output measured by thoracic electrical bioimpdenace with that measured by multigated radionuclide equilibrium cardiography. Patients and methods: CO studies were performed sequentially at a single sitting by TEB and RNEC methods among patients with cardiac symptoms referred for radionuclide study as part of their evaluation. TEB CO was measured by placing two pairs of electrodes on either side of neck and two other pairs on either side of the lower chest. Stroke volume was estimated from the sequential changes in transthoracic electrical bioimpedance induced by rhythmic aortic blood flow, using Kubicek equation. RNEC-CO was measured by intravenous injection of radio-active Technitiumtagged RBCs followed by ECG gated blood pool imaging over the chest (MUGA study). Bland-Altman analysis was used to compare the measurements. Results: A total of 32 subjects with proven or suspected ischemic heart disease, but without overt cardiac failure, edema or arrhythmias were studied (M:F::26:6; mean age: 48 ± 12 years). The mean TEB-CO was 3.54 ± 1.052 l/min and mean RNEC-CO was 3.907 ± 0.952 l/min. Correlation coefficient (r) for these measurements was 0.67 (p <0.01), with bias: -0.421 l/min; precision: 1.557 l/min; and percentage error of measurement: 42.35{\%}. Conclusions: This study observed a moderate correlation between TEB and RNEC methods of CO measurement. Further studies are indicated to explore the relative utility of TEB in comparison with RNEC as well as other methods of CO measurement before considering its use in patients with ischemic heart disease.",
keywords = "Cardiac output, MUGA, Multigated equilibrium radionuclide cardiography, Thoracic electrical bioimpedance",
author = "Gujjar, {Arunodaya R.} and K. Muralidhar and Abhijit Bhandopadhyaya and Sathyaprabha, {T. N.} and P. Janaki and Mahalla, {B. K.} and Ratan Gupta and Sanjay Banakal and Jairaj, {P. S.}",
year = "2010",
month = "4",
doi = "10.1007/s10877-010-9225-5",
language = "English",
volume = "24",
pages = "155--159",
journal = "Journal of Clinical Monitoring and Computing",
issn = "1387-1307",
publisher = "Springer Netherlands",
number = "2",

}

TY - JOUR

T1 - Transthoracic electrical bioimpedence cardiac output

T2 - Comparison with multigated equillibrium radionuclide cardiography

AU - Gujjar, Arunodaya R.

AU - Muralidhar, K.

AU - Bhandopadhyaya, Abhijit

AU - Sathyaprabha, T. N.

AU - Janaki, P.

AU - Mahalla, B. K.

AU - Gupta, Ratan

AU - Banakal, Sanjay

AU - Jairaj, P. S.

PY - 2010/4

Y1 - 2010/4

N2 - Introduction: Thoracic electrical bioimpedance (TEB) for measuring cardiac output (CO) is being explored increasingly as an alternative to pulmonary artery catheter. The major advantage of this technology is that it is non-invasive and easy to perform. Several studies have compared it to thermodilution cardiac output using PA catheter, with variable correlation. Multigated radionuclide equilibrium cardiography (RNEC) method of cardiac output measurement is known to be reliable. Objective: To compare cardiac output measured by thoracic electrical bioimpdenace with that measured by multigated radionuclide equilibrium cardiography. Patients and methods: CO studies were performed sequentially at a single sitting by TEB and RNEC methods among patients with cardiac symptoms referred for radionuclide study as part of their evaluation. TEB CO was measured by placing two pairs of electrodes on either side of neck and two other pairs on either side of the lower chest. Stroke volume was estimated from the sequential changes in transthoracic electrical bioimpedance induced by rhythmic aortic blood flow, using Kubicek equation. RNEC-CO was measured by intravenous injection of radio-active Technitiumtagged RBCs followed by ECG gated blood pool imaging over the chest (MUGA study). Bland-Altman analysis was used to compare the measurements. Results: A total of 32 subjects with proven or suspected ischemic heart disease, but without overt cardiac failure, edema or arrhythmias were studied (M:F::26:6; mean age: 48 ± 12 years). The mean TEB-CO was 3.54 ± 1.052 l/min and mean RNEC-CO was 3.907 ± 0.952 l/min. Correlation coefficient (r) for these measurements was 0.67 (p <0.01), with bias: -0.421 l/min; precision: 1.557 l/min; and percentage error of measurement: 42.35%. Conclusions: This study observed a moderate correlation between TEB and RNEC methods of CO measurement. Further studies are indicated to explore the relative utility of TEB in comparison with RNEC as well as other methods of CO measurement before considering its use in patients with ischemic heart disease.

AB - Introduction: Thoracic electrical bioimpedance (TEB) for measuring cardiac output (CO) is being explored increasingly as an alternative to pulmonary artery catheter. The major advantage of this technology is that it is non-invasive and easy to perform. Several studies have compared it to thermodilution cardiac output using PA catheter, with variable correlation. Multigated radionuclide equilibrium cardiography (RNEC) method of cardiac output measurement is known to be reliable. Objective: To compare cardiac output measured by thoracic electrical bioimpdenace with that measured by multigated radionuclide equilibrium cardiography. Patients and methods: CO studies were performed sequentially at a single sitting by TEB and RNEC methods among patients with cardiac symptoms referred for radionuclide study as part of their evaluation. TEB CO was measured by placing two pairs of electrodes on either side of neck and two other pairs on either side of the lower chest. Stroke volume was estimated from the sequential changes in transthoracic electrical bioimpedance induced by rhythmic aortic blood flow, using Kubicek equation. RNEC-CO was measured by intravenous injection of radio-active Technitiumtagged RBCs followed by ECG gated blood pool imaging over the chest (MUGA study). Bland-Altman analysis was used to compare the measurements. Results: A total of 32 subjects with proven or suspected ischemic heart disease, but without overt cardiac failure, edema or arrhythmias were studied (M:F::26:6; mean age: 48 ± 12 years). The mean TEB-CO was 3.54 ± 1.052 l/min and mean RNEC-CO was 3.907 ± 0.952 l/min. Correlation coefficient (r) for these measurements was 0.67 (p <0.01), with bias: -0.421 l/min; precision: 1.557 l/min; and percentage error of measurement: 42.35%. Conclusions: This study observed a moderate correlation between TEB and RNEC methods of CO measurement. Further studies are indicated to explore the relative utility of TEB in comparison with RNEC as well as other methods of CO measurement before considering its use in patients with ischemic heart disease.

KW - Cardiac output

KW - MUGA

KW - Multigated equilibrium radionuclide cardiography

KW - Thoracic electrical bioimpedance

UR - http://www.scopus.com/inward/record.url?scp=77953325637&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953325637&partnerID=8YFLogxK

U2 - 10.1007/s10877-010-9225-5

DO - 10.1007/s10877-010-9225-5

M3 - Article

VL - 24

SP - 155

EP - 159

JO - Journal of Clinical Monitoring and Computing

JF - Journal of Clinical Monitoring and Computing

SN - 1387-1307

IS - 2

ER -