TY - JOUR
T1 - Transthoracic electrical bioimpedence cardiac output
T2 - Comparison with multigated equillibrium radionuclide cardiography
AU - Gujjar, Arunodaya R.
AU - Muralidhar, K.
AU - Bhandopadhyaya, Abhijit
AU - Sathyaprabha, T. N.
AU - Janaki, P.
AU - Mahalla, B. K.
AU - Gupta, Ratan
AU - Banakal, Sanjay
AU - Jairaj, P. S.
N1 - Funding Information:
This research was supported by Larsen & Toubro (India) Ltd., Electrical & Electronics Division, Mysore, India. The sponsors however did not influence the study design, execution, analysis or conclusions. The authors acknowledge Prof. Jindal GD, Bhabha Atomic Research Institute, Mumbai, India for expert advice and guidance and the Nursing and Technical staff at Narayana Hrudayalaya Institute of Cardiac Sciences for their support.
PY - 2010/4
Y1 - 2010/4
N2 - Introduction: Thoracic electrical bioimpedance (TEB) for measuring cardiac output (CO) is being explored increasingly as an alternative to pulmonary artery catheter. The major advantage of this technology is that it is non-invasive and easy to perform. Several studies have compared it to thermodilution cardiac output using PA catheter, with variable correlation. Multigated radionuclide equilibrium cardiography (RNEC) method of cardiac output measurement is known to be reliable. Objective: To compare cardiac output measured by thoracic electrical bioimpdenace with that measured by multigated radionuclide equilibrium cardiography. Patients and methods: CO studies were performed sequentially at a single sitting by TEB and RNEC methods among patients with cardiac symptoms referred for radionuclide study as part of their evaluation. TEB CO was measured by placing two pairs of electrodes on either side of neck and two other pairs on either side of the lower chest. Stroke volume was estimated from the sequential changes in transthoracic electrical bioimpedance induced by rhythmic aortic blood flow, using Kubicek equation. RNEC-CO was measured by intravenous injection of radio-active Technitiumtagged RBCs followed by ECG gated blood pool imaging over the chest (MUGA study). Bland-Altman analysis was used to compare the measurements. Results: A total of 32 subjects with proven or suspected ischemic heart disease, but without overt cardiac failure, edema or arrhythmias were studied (M:F::26:6; mean age: 48 ± 12 years). The mean TEB-CO was 3.54 ± 1.052 l/min and mean RNEC-CO was 3.907 ± 0.952 l/min. Correlation coefficient (r) for these measurements was 0.67 (p < 0.01), with bias: -0.421 l/min; precision: 1.557 l/min; and percentage error of measurement: 42.35%. Conclusions: This study observed a moderate correlation between TEB and RNEC methods of CO measurement. Further studies are indicated to explore the relative utility of TEB in comparison with RNEC as well as other methods of CO measurement before considering its use in patients with ischemic heart disease.
AB - Introduction: Thoracic electrical bioimpedance (TEB) for measuring cardiac output (CO) is being explored increasingly as an alternative to pulmonary artery catheter. The major advantage of this technology is that it is non-invasive and easy to perform. Several studies have compared it to thermodilution cardiac output using PA catheter, with variable correlation. Multigated radionuclide equilibrium cardiography (RNEC) method of cardiac output measurement is known to be reliable. Objective: To compare cardiac output measured by thoracic electrical bioimpdenace with that measured by multigated radionuclide equilibrium cardiography. Patients and methods: CO studies were performed sequentially at a single sitting by TEB and RNEC methods among patients with cardiac symptoms referred for radionuclide study as part of their evaluation. TEB CO was measured by placing two pairs of electrodes on either side of neck and two other pairs on either side of the lower chest. Stroke volume was estimated from the sequential changes in transthoracic electrical bioimpedance induced by rhythmic aortic blood flow, using Kubicek equation. RNEC-CO was measured by intravenous injection of radio-active Technitiumtagged RBCs followed by ECG gated blood pool imaging over the chest (MUGA study). Bland-Altman analysis was used to compare the measurements. Results: A total of 32 subjects with proven or suspected ischemic heart disease, but without overt cardiac failure, edema or arrhythmias were studied (M:F::26:6; mean age: 48 ± 12 years). The mean TEB-CO was 3.54 ± 1.052 l/min and mean RNEC-CO was 3.907 ± 0.952 l/min. Correlation coefficient (r) for these measurements was 0.67 (p < 0.01), with bias: -0.421 l/min; precision: 1.557 l/min; and percentage error of measurement: 42.35%. Conclusions: This study observed a moderate correlation between TEB and RNEC methods of CO measurement. Further studies are indicated to explore the relative utility of TEB in comparison with RNEC as well as other methods of CO measurement before considering its use in patients with ischemic heart disease.
KW - Cardiac output
KW - MUGA
KW - Multigated equilibrium radionuclide cardiography
KW - Thoracic electrical bioimpedance
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U2 - 10.1007/s10877-010-9225-5
DO - 10.1007/s10877-010-9225-5
M3 - Article
C2 - 20229061
AN - SCOPUS:77953325637
SN - 1387-1307
VL - 24
SP - 155
EP - 159
JO - Journal of Clinical Monitoring and Computing
JF - Journal of Clinical Monitoring and Computing
IS - 2
ER -