Transient myeloproliferative disorder and Down syndrome: Is there a link?

Zenaida S. Reyes, Wafa Bashir, Anil Pathare

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

An extremely premature male neonate presented with an unusual multisystem dysfunction within the first 24 to 48 hours of life. The unfolding of clinical events and investigations revealed a transient myeloproliferative disorder (TMD). TMD was the main indication for karyotyping of this premature infant without clinical symptoms of Down syndrome. The awareness of TMD in a newborn warrants karyotype analysis to look for trisomy 21 and a close surveillance because of its potential progression to true leukaemia.

Original languageEnglish
Pages (from-to)498-502
Number of pages5
JournalSultan Qaboos University Medical Journal
Volume12
Issue number4
Publication statusPublished - Nov 2012

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Keywords

  • Acute myelogenous leukemia (AML)
  • Case report
  • Down syndrome
  • Extreme premature
  • GATA1
  • Oman
  • Transient myeloproliferative disorder

ASJC Scopus subject areas

  • Medicine(all)

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