Transfusion associated HIV infection in patients with haematologic disorders in southern India

V. Bhushan, M. Chandy*, P. G. Babu, D. Dennison, A. Srivastava, N. K. Saraswathi, T. J. John

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Seventy patients with congenital coagulation disorders (group A) and 202 other patients (group B) attending the Haematology clinic at the Christian Medical College and Hospital, Vellore (India) were screened for HIV infection between March 1989 and April 1991. Fifty five patients in group A and 131 patients in group B had received blood or blood products in the past. Nineteen transfused patients (9 in group A and 10 in group B) had received blood or blood products exclusively from the hospital blood bank and none of them was HIV infected. Among the remaining 167 transfused patients, 14 (30.4%) of the 46 patients in group A and 6 (4.9%) of the 121 patients in group B were found to be positive for HIV. In group A, 13 of the 14 infected patients had received commercially available cryoprecipitate which was thus found to be the most frequent source of infection. In group B the source of infection was most probably unscreened HIV infected blood which was transfused.

Original languageEnglish
Pages (from-to)57-60
Number of pages4
JournalIndian Journal of Medical Research
Volume99
Issue numberFEB.
Publication statusPublished - 1994
Externally publishedYes

Keywords

  • AIDS
  • Blood transfusion
  • Commercial cryoprecipitate
  • HIV infection
  • Haematologic disorders
  • South India

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology

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