Abstract
To determine whether the sympathetic nervous system plays any role in the inter-individual variation of cardiovascular response to hypoxia in newborns, neonatal heart rate variability (HRV) analysis was used to assess autonomic response during hypoxia in piglets. Due to the nonstationary nature of HRV signals and the inaccuracy in pre-defined neonatal HRV frequency bands using standard spectral methods, we applied time-frequency distribution analysis to assess neonatal HRV. Although sympathetic activity was initially enhanced to stimulate the cardiac compensation, it did not account for the variation of cardiovascular response since the power of low frequency component in HRV neither showed corresponding changes with the heart rate nor had any correlation with the brain injury. This may be attributed to immaturity of the neural pathway.
| Original language | English |
|---|---|
| Title of host publication | Computing in Cardiology 2011, CinC 2011 |
| Pages | 701-704 |
| Number of pages | 4 |
| Volume | 38 |
| Publication status | Published - 2011 |
| Event | Computing in Cardiology 2011, CinC 2011 - Hangzhou, China Duration: Sep 18 2011 → Sep 21 2011 |
Other
| Other | Computing in Cardiology 2011, CinC 2011 |
|---|---|
| Country | China |
| City | Hangzhou |
| Period | 9/18/11 → 9/21/11 |
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ASJC Scopus subject areas
- Computer Science(all)
- Cardiology and Cardiovascular Medicine
Cite this
Time-frequency analysis of heart rate variability in neonatal piglets exposed to hypoxia. / Dong, Shiying; Mesbah, Mostefa; Lingwood, Barbara E.; O'Toole, John M.; Boashash, Boualem.
Computing in Cardiology 2011, CinC 2011. Vol. 38 2011. p. 701-704 6164662.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Time-frequency analysis of heart rate variability in neonatal piglets exposed to hypoxia
AU - Dong, Shiying
AU - Mesbah, Mostefa
AU - Lingwood, Barbara E.
AU - O'Toole, John M.
AU - Boashash, Boualem
PY - 2011
Y1 - 2011
N2 - To determine whether the sympathetic nervous system plays any role in the inter-individual variation of cardiovascular response to hypoxia in newborns, neonatal heart rate variability (HRV) analysis was used to assess autonomic response during hypoxia in piglets. Due to the nonstationary nature of HRV signals and the inaccuracy in pre-defined neonatal HRV frequency bands using standard spectral methods, we applied time-frequency distribution analysis to assess neonatal HRV. Although sympathetic activity was initially enhanced to stimulate the cardiac compensation, it did not account for the variation of cardiovascular response since the power of low frequency component in HRV neither showed corresponding changes with the heart rate nor had any correlation with the brain injury. This may be attributed to immaturity of the neural pathway.
AB - To determine whether the sympathetic nervous system plays any role in the inter-individual variation of cardiovascular response to hypoxia in newborns, neonatal heart rate variability (HRV) analysis was used to assess autonomic response during hypoxia in piglets. Due to the nonstationary nature of HRV signals and the inaccuracy in pre-defined neonatal HRV frequency bands using standard spectral methods, we applied time-frequency distribution analysis to assess neonatal HRV. Although sympathetic activity was initially enhanced to stimulate the cardiac compensation, it did not account for the variation of cardiovascular response since the power of low frequency component in HRV neither showed corresponding changes with the heart rate nor had any correlation with the brain injury. This may be attributed to immaturity of the neural pathway.
UR - http://www.scopus.com/inward/record.url?scp=84859939363&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859939363&partnerID=8YFLogxK
M3 - Conference contribution
SN - 9781457706127
VL - 38
SP - 701
EP - 704
BT - Computing in Cardiology 2011, CinC 2011
ER -