The underlying mechanism of action for various medicinal properties of Piper betle (betel)

H. Haslan, F. H. Suhaimi, Zar Chi Thent, S. Das*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Piper betle (betel) plant belongs to the Piperaceae family. Piper. betle is widely known for its potent medicinal properties. Various active compounds are present in Piper. betle such as allylpyrocatechol, hydroxychavicol, piperbetol, ethylpiperbetol, piperol A, piperol B, chavibetol, and alkaloids which account for these beneficial medicinal properties. In the present narrative review, we looked into the various active compounds present in the Piper betle and attempted to understand their underlying mechanism of action. Proper understanding of the molecular biology involving the mechanism of action may help in better drug formulation and provide better therapeutic actions in the field of alternative and complementary medicine.

Original languageEnglish
Pages (from-to)208-214
Number of pages7
JournalClinica Terapeutica
Issue number5
Publication statusPublished - 2015
Externally publishedYes


  • Analgesicisolated
  • Anti-inflammatory
  • Anticancer
  • Antidiabetic
  • Antioxidant
  • Cardioprotective
  • Gastroprotective
  • Hepatoprotective
  • Piper betle
  • Radioprotective

ASJC Scopus subject areas

  • Medicine(all)

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