TY - JOUR
T1 - The role of houseflies in cholera transmission
AU - Al-Shanfari, Shaimaa
AU - Elmojtaba, Ibrahim M.
AU - Alsalti, Nasser
N1 - Funding Information:
The authors would like to acknowledge financial support from Sultan Qaboos university, Oman and United Arab Emirates University, UAE through the joint research grant no. CL/SQUUAEU/17/01.
Funding Information:
The authors would like to acknowledge financial support from Sultan Qaboos University, Oman and United Arab Emirates University, UAE through the joint research grant no. CL/SQU-UAEU/17/01.
Publisher Copyright:
© 2019 the author(s).
PY - 2019
Y1 - 2019
N2 - In this paper, we propose and analyse a mathematical model that describes the dynamics of Cholera. The main aim of this model is to investigate the role of houseflies in the transmission of Cholera. Our analysis showed that the disease free equilibrium is globally asymptotically stable whenever the basic reproduction number is less than unity; and unstable otherwise; and our model posses only one endemic equilibrium which is locally asymptotically stable whenever basic reproduction number is greater than unity. Our sensitivity analysis showed that the basic reproduction number is very sensitive to ingesting vibrios rate from aquatic environment by vectors, the rate of contribution to V. cholera in the aquatic environment and the death rate of vector and death rate of vibrios in aquatic environment which indicates that the vector (i.e. the houseflies) play a very important role in the transmission procedure.Numerically, we shown that the rate of water contamination by infectious people shedding V. cholera into the environment has no impact in the infection because it depends on both bacteria shedding of the infected individuals and the level of sanitation in the environment and since the environment is safe, then it is obviously has no effects. In addition, if the contact rate of vectors with contaminated water is high in the presence of increased contribution of each infected vector to the aquatic environment then cholera will persist in the population. Therefore, to obtain a significant and effective control, the contribution of each infected vector to the aquatic environment and the rate of exposure to contaminated water must be reduced.
AB - In this paper, we propose and analyse a mathematical model that describes the dynamics of Cholera. The main aim of this model is to investigate the role of houseflies in the transmission of Cholera. Our analysis showed that the disease free equilibrium is globally asymptotically stable whenever the basic reproduction number is less than unity; and unstable otherwise; and our model posses only one endemic equilibrium which is locally asymptotically stable whenever basic reproduction number is greater than unity. Our sensitivity analysis showed that the basic reproduction number is very sensitive to ingesting vibrios rate from aquatic environment by vectors, the rate of contribution to V. cholera in the aquatic environment and the death rate of vector and death rate of vibrios in aquatic environment which indicates that the vector (i.e. the houseflies) play a very important role in the transmission procedure.Numerically, we shown that the rate of water contamination by infectious people shedding V. cholera into the environment has no impact in the infection because it depends on both bacteria shedding of the infected individuals and the level of sanitation in the environment and since the environment is safe, then it is obviously has no effects. In addition, if the contact rate of vectors with contaminated water is high in the presence of increased contribution of each infected vector to the aquatic environment then cholera will persist in the population. Therefore, to obtain a significant and effective control, the contribution of each infected vector to the aquatic environment and the rate of exposure to contaminated water must be reduced.
KW - Basic reproduction number
KW - Bifurcation analysis
KW - Cholera model
KW - Sensitivity analysis
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U2 - 10.28919/cmbn/4281
DO - 10.28919/cmbn/4281
M3 - Article
AN - SCOPUS:85078629512
SN - 2052-2541
VL - 2019
JO - Communications in Mathematical Biology and Neuroscience
JF - Communications in Mathematical Biology and Neuroscience
M1 - 31
ER -