The prognostic determinants of gastric cancer treatment outcome in Omani Arab patients

M. S. Al-Moundhri, B. Al-Bahrani, I. A. Burney, V. Nirmala, A. Al-Madhani, K. Al-Mawaly, M. Al-Nabhani, V. Thomas, S. S. Ganguly, C. S. Grant

Research output: Contribution to journalArticle

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Abstract

Background: Gastric cancer is the most common cancer in Oman and a leading cause of cancer death. The variation in survival rates between countries and ethnic groups has been attributed to early detection policies, differences in clinicopathological features, treatment approaches, and biological characteristics. There were no previous reports on gastric cancer from Oman and very few studies on Asian Arabs. Aim: To evaluate the impact of clinicopathological and treatment variables on the survival prospects of Omani Arab patients diagnosed with gastric cancer. Methods: The medical records of 339 Omani Arab patients diagnosed with invasive gastric adenocarcinoma during the period 1993-2004 were retrospectively reviewed. The relative importance of clinicopathological features and surgical and medical treatments were assessed using univariate and multivariate analyses. Results: Most patients had distal ulcerating-type gastric cancer and presented at advanced stages. The median survival time for the entire cohort was 12 months (95% CI 9.7-14.4) with a 5-year overall survival rate of 16.7%. On univariate analysis of 237 patients who underwent surgical resection, the following positive prognostic factors emerged as significant: early overall TNM stage, early T stage, negative lymph nodes, tumor size

Original languageEnglish
Pages (from-to)90-96
Number of pages7
JournalOncology
Volume70
Issue number2
DOIs
Publication statusPublished - May 2006

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Stomach Neoplasms
Oman
Survival Rate
Neoplasms
Survival
Ethnic Groups
Medical Records
Cause of Death
Stomach
Adenocarcinoma
Therapeutics
Multivariate Analysis
Lymph Nodes

Keywords

  • Gastric cancer
  • Stomach

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

The prognostic determinants of gastric cancer treatment outcome in Omani Arab patients. / Al-Moundhri, M. S.; Al-Bahrani, B.; Burney, I. A.; Nirmala, V.; Al-Madhani, A.; Al-Mawaly, K.; Al-Nabhani, M.; Thomas, V.; Ganguly, S. S.; Grant, C. S.

In: Oncology, Vol. 70, No. 2, 05.2006, p. 90-96.

Research output: Contribution to journalArticle

Al-Moundhri, MS, Al-Bahrani, B, Burney, IA, Nirmala, V, Al-Madhani, A, Al-Mawaly, K, Al-Nabhani, M, Thomas, V, Ganguly, SS & Grant, CS 2006, 'The prognostic determinants of gastric cancer treatment outcome in Omani Arab patients', Oncology, vol. 70, no. 2, pp. 90-96. https://doi.org/10.1159/000092584
Al-Moundhri, M. S. ; Al-Bahrani, B. ; Burney, I. A. ; Nirmala, V. ; Al-Madhani, A. ; Al-Mawaly, K. ; Al-Nabhani, M. ; Thomas, V. ; Ganguly, S. S. ; Grant, C. S. / The prognostic determinants of gastric cancer treatment outcome in Omani Arab patients. In: Oncology. 2006 ; Vol. 70, No. 2. pp. 90-96.
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