The outcome of treatment of breast cancer in a developing country - Oman

A. Al-Moundhri, B. Al-Bahrani, I. Pervez, S. S. Ganguly, V. Nirmala, A. Al-Madhani, K. Al-Mawalay, C. Grant

Research output: Contribution to journalArticle

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Abstract

The aim of the present study was to evaluate the outcome of treatment of breast cancer in Oman with an analysis of clinico-pathological features, treatment modalities utilized, and prognostic factors. One hundred fifty-two breast cancer patients diagnosed between January 1996 and June 2002 were evaluated retrospectively. Their mean age was 48.5 (S.D.±10.8) years, and 48% of the female patients were premenopausal. The mean tumor size according to pathology was 4.6 (S.D. 3.29) cm, and 34.9% and 15.8% of patients had stage III or IV disease, respectively. Only 26.3% of the patients had breast-conserving surgery, and neoadjuvant chemotherapy was underutilized. The overall 5-year relapse-free survival (RFS) and overall (OS) survival rates were 62% and 64%, respectively. On multivariate analysis, axillary lymph node involvement and tumor differentiation were predictive of RFS and OS, respectively. Thus, breast cancer patients in Oman present with advanced stages of the disease at younger ages than their counterparts in the West and have lower survival rates. Increasing awareness and the introduction of screening programs and of a multidisciplinary approach are essential in Oman and other developing countries to improve the outcome of treatment.

Original languageEnglish
Pages (from-to)139-145
Number of pages7
JournalBreast
Volume13
Issue number2
DOIs
Publication statusPublished - Apr 2004

Fingerprint

Oman
Developing Countries
Breast Neoplasms
Survival Rate
Recurrence
Survival
Segmental Mastectomy
Neoplasms
Multivariate Analysis
Lymph Nodes
Pathology
Drug Therapy

Keywords

  • Breast cancer
  • Developing country
  • Oman

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

The outcome of treatment of breast cancer in a developing country - Oman. / Al-Moundhri, A.; Al-Bahrani, B.; Pervez, I.; Ganguly, S. S.; Nirmala, V.; Al-Madhani, A.; Al-Mawalay, K.; Grant, C.

In: Breast, Vol. 13, No. 2, 04.2004, p. 139-145.

Research output: Contribution to journalArticle

Al-Moundhri, A, Al-Bahrani, B, Pervez, I, Ganguly, SS, Nirmala, V, Al-Madhani, A, Al-Mawalay, K & Grant, C 2004, 'The outcome of treatment of breast cancer in a developing country - Oman', Breast, vol. 13, no. 2, pp. 139-145. https://doi.org/10.1016/j.breast.2003.10.001
Al-Moundhri, A. ; Al-Bahrani, B. ; Pervez, I. ; Ganguly, S. S. ; Nirmala, V. ; Al-Madhani, A. ; Al-Mawalay, K. ; Grant, C. / The outcome of treatment of breast cancer in a developing country - Oman. In: Breast. 2004 ; Vol. 13, No. 2. pp. 139-145.
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