The islamic ethics of mitochondria transplantation

Anke Iman Bouzenita, Mohamed Elwathig S. Mirghani, Irwandi Jaswir

Research output: Contribution to journalArticle

Abstract

Biotechnology has opened a new chapter with the advent of mitochondria transplantation for cell-based therapy. Mitochondrial transplantation has successfully led to birth; however, cytoplasmic transplantation has caused apprehension since the mixing of human ooplasm from two different maternal sources may generate mitochondrial DNA (mtDNA) heteroplasmy in the offspring. Most Islamic legal verdicts on human cloning and somatic cell transfer are explicit as to its prohibition, due to the change of creation, mixing of lineage and other evaluations. Is mitochondria transplantation equivalent to human cloning in that genetic information is proliferated and does it, therefore, take the same legal rule? Are there possible benefits (maşālih) for medical treatment that may render mitochondria transplantation permissible, or are possible harms (mafasid) overweighing? Or is it a completely different procedure, taking a different rule? The paper will investigate into these questions and discuss the dimensions of Islamic ethics on the issue.

Original languageEnglish
Pages (from-to)42-46
Number of pages5
JournalIIUM Engineering Journal
Volume18
Issue number2
Publication statusPublished - Jan 1 2017

Fingerprint

Transplantation
Mitochondria
Cloning
Biotechnology
Mitochondrial DNA
DNA
Cell
Therapy
Ethics
Evaluation
Human

Keywords

  • Benefits (ma?ali?)
  • DNA
  • Genome
  • Harms (mafasid)
  • Heteroplasmy
  • Islamic ethics
  • Mitochondria
  • Organelle

ASJC Scopus subject areas

  • Engineering(all)
  • Chemical Engineering(all)
  • Computer Science(all)
  • Applied Mathematics

Cite this

Bouzenita, A. I., Mirghani, M. E. S., & Jaswir, I. (2017). The islamic ethics of mitochondria transplantation. IIUM Engineering Journal, 18(2), 42-46.

The islamic ethics of mitochondria transplantation. / Bouzenita, Anke Iman; Mirghani, Mohamed Elwathig S.; Jaswir, Irwandi.

In: IIUM Engineering Journal, Vol. 18, No. 2, 01.01.2017, p. 42-46.

Research output: Contribution to journalArticle

Bouzenita, AI, Mirghani, MES & Jaswir, I 2017, 'The islamic ethics of mitochondria transplantation', IIUM Engineering Journal, vol. 18, no. 2, pp. 42-46.
Bouzenita, Anke Iman ; Mirghani, Mohamed Elwathig S. ; Jaswir, Irwandi. / The islamic ethics of mitochondria transplantation. In: IIUM Engineering Journal. 2017 ; Vol. 18, No. 2. pp. 42-46.
@article{9a325ca19cad485488a8cb9974b27a22,
title = "The islamic ethics of mitochondria transplantation",
abstract = "Biotechnology has opened a new chapter with the advent of mitochondria transplantation for cell-based therapy. Mitochondrial transplantation has successfully led to birth; however, cytoplasmic transplantation has caused apprehension since the mixing of human ooplasm from two different maternal sources may generate mitochondrial DNA (mtDNA) heteroplasmy in the offspring. Most Islamic legal verdicts on human cloning and somatic cell transfer are explicit as to its prohibition, due to the change of creation, mixing of lineage and other evaluations. Is mitochondria transplantation equivalent to human cloning in that genetic information is proliferated and does it, therefore, take the same legal rule? Are there possible benefits (maşālih) for medical treatment that may render mitochondria transplantation permissible, or are possible harms (mafasid) overweighing? Or is it a completely different procedure, taking a different rule? The paper will investigate into these questions and discuss the dimensions of Islamic ethics on the issue.",
keywords = "Benefits (ma?ali?), DNA, Genome, Harms (mafasid), Heteroplasmy, Islamic ethics, Mitochondria, Organelle",
author = "Bouzenita, {Anke Iman} and Mirghani, {Mohamed Elwathig S.} and Irwandi Jaswir",
year = "2017",
month = "1",
day = "1",
language = "English",
volume = "18",
pages = "42--46",
journal = "IIUM Engineering Journal",
issn = "1511-788X",
publisher = "International Islamic University Malaysia",
number = "2",

}

TY - JOUR

T1 - The islamic ethics of mitochondria transplantation

AU - Bouzenita, Anke Iman

AU - Mirghani, Mohamed Elwathig S.

AU - Jaswir, Irwandi

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Biotechnology has opened a new chapter with the advent of mitochondria transplantation for cell-based therapy. Mitochondrial transplantation has successfully led to birth; however, cytoplasmic transplantation has caused apprehension since the mixing of human ooplasm from two different maternal sources may generate mitochondrial DNA (mtDNA) heteroplasmy in the offspring. Most Islamic legal verdicts on human cloning and somatic cell transfer are explicit as to its prohibition, due to the change of creation, mixing of lineage and other evaluations. Is mitochondria transplantation equivalent to human cloning in that genetic information is proliferated and does it, therefore, take the same legal rule? Are there possible benefits (maşālih) for medical treatment that may render mitochondria transplantation permissible, or are possible harms (mafasid) overweighing? Or is it a completely different procedure, taking a different rule? The paper will investigate into these questions and discuss the dimensions of Islamic ethics on the issue.

AB - Biotechnology has opened a new chapter with the advent of mitochondria transplantation for cell-based therapy. Mitochondrial transplantation has successfully led to birth; however, cytoplasmic transplantation has caused apprehension since the mixing of human ooplasm from two different maternal sources may generate mitochondrial DNA (mtDNA) heteroplasmy in the offspring. Most Islamic legal verdicts on human cloning and somatic cell transfer are explicit as to its prohibition, due to the change of creation, mixing of lineage and other evaluations. Is mitochondria transplantation equivalent to human cloning in that genetic information is proliferated and does it, therefore, take the same legal rule? Are there possible benefits (maşālih) for medical treatment that may render mitochondria transplantation permissible, or are possible harms (mafasid) overweighing? Or is it a completely different procedure, taking a different rule? The paper will investigate into these questions and discuss the dimensions of Islamic ethics on the issue.

KW - Benefits (ma?ali?)

KW - DNA

KW - Genome

KW - Harms (mafasid)

KW - Heteroplasmy

KW - Islamic ethics

KW - Mitochondria

KW - Organelle

UR - http://www.scopus.com/inward/record.url?scp=85036509324&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85036509324&partnerID=8YFLogxK

M3 - Article

VL - 18

SP - 42

EP - 46

JO - IIUM Engineering Journal

JF - IIUM Engineering Journal

SN - 1511-788X

IS - 2

ER -