The haempeptides from cytochrome c. Exploring the basic chemistry of the iron porphyrins and modelling aspects of the haemoproteins

Helder M. Marques, Musa S. Shongwe, Orde Q. Munro, Timothy J. Egan

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The haempeptides from cytochrome c, obtained by proteolysis of the parent protein, contain an iron(III) porphyrin linked by thioether bridges to a polypeptide chain. They provide an opportunity for exploring aspects of the fundamental chemistry of an iron(III) porphyrin in which one of the axial coordination sites of the metal ion is occupied by a His residue (from the parent protein) and the other contains a readily-replaced H2O molecule. The preparation, solution properties and electronic properties of these important models for the haemoproteins are reviewed and facets of their reactions are considered.

Original languageEnglish
Pages (from-to)166-180
Number of pages15
JournalSouth African Journal of Chemistry
Volume50
Issue number4
Publication statusPublished - Dec 1997

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Porphyrins
Cytochromes c
Iron
Proteolysis
Sulfides
Electronic properties
Metal ions
Proteins
Peptides
Molecules

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

The haempeptides from cytochrome c. Exploring the basic chemistry of the iron porphyrins and modelling aspects of the haemoproteins. / Marques, Helder M.; Shongwe, Musa S.; Munro, Orde Q.; Egan, Timothy J.

In: South African Journal of Chemistry, Vol. 50, No. 4, 12.1997, p. 166-180.

Research output: Contribution to journalArticle

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