The effect of thiamin supplementation on the thiamin status of turkey poults with ethanol-induced cardiomegaly

Badreldin H. Ali, Caroline M. Czarnecki

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Abstract

1. Turkey poults were treated with graded doses (0-5% v/v) of ethanol for 6 weeks. Some birds were concomittantly injected intramuscularly with thiamin. 2. Erythrocyte transketolase (TK) activity was significantly decreased and the erythrocyte pyrophosphate (TPP) effect and blood concentrations of lactate and pyruvate were statistically greater in all ethanol-treated poults by 42 days. 3. Thiamin restored TK activity to normal levels and decreased the TPP effect and blood concentrations of lactate and pyruvate in ethanol poults. 4. Thiamin mitigated ethanol-induced cardiomyopathy in some 4-5% ethanol poults. 5. Thiamin had no significant effect on any of these parameters in control birds treated with thiamin.

Original languageEnglish
Pages (from-to)531-533
Number of pages3
JournalGeneral Pharmacology
Volume18
Issue number5
DOIs
Publication statusPublished - 1987

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ASJC Scopus subject areas

  • Pharmacology

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