The application of 7-chloro-4-nitrobenzoxadiazole and 4-fluoro-7-nitro-2,1,3-benzoxadiazole for the analysis of amines and amino acids using high-performance liquid chromatography

Abdalla A. Elbashir, F. E O Suliman, Hassan Y. Aboul-Enein

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8 Citations (Scopus)


This paper reviews analytical methods, instrumental developments and applications for derivatization of amines and amino acids with 7-Chloro-4-nitrobenzoxadiazole (NBD-Cl) and 4-Fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F) using high performance liquid chromatography (HPLC). Discussion of the literature related to the application from 2001 to 2010 is presented.

Original languageEnglish
Pages (from-to)679-697
Number of pages19
JournalGazi University Journal of Science
Issue number4
Publication statusPublished - 2011



  • 2D-HPLC
  • Amines and Amino acids
  • HPLC
  • NBD-Cl
  • NBD-F

ASJC Scopus subject areas

  • General
  • Engineering(all)

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