The anti-diamine oxidase effect of furazolidone in rabbits

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1. Furazolidone (50 mg/kg for 5 days) given orally to rabbits produced a significant inhibition of diamine oxidase (DAO) activity in various tissues. 2. Suppression of the rabbits' gut flora by oxytetracycline treatment significantly reduced the DAO inhibitory effect of furazolidone, suggesting that the gut flora may be involved in the transformation of furazolidone into an active DAO inhibitor.

Original languageEnglish
Pages (from-to)109-110
Number of pages2
JournalComparative Biochemistry and Physiology. Part C, Comparative
Issue number1
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Immunology
  • Pharmacology

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