TY - JOUR
T1 - The anti-diamine oxidase effect of furazolidone in rabbits
AU - Ali, B. H.
PY - 1983
Y1 - 1983
N2 - 1. Furazolidone (50 mg/kg for 5 days) given orally to rabbits produced a significant inhibition of diamine oxidase (DAO) activity in various tissues. 2. Suppression of the rabbits' gut flora by oxytetracycline treatment significantly reduced the DAO inhibitory effect of furazolidone, suggesting that the gut flora may be involved in the transformation of furazolidone into an active DAO inhibitor.
AB - 1. Furazolidone (50 mg/kg for 5 days) given orally to rabbits produced a significant inhibition of diamine oxidase (DAO) activity in various tissues. 2. Suppression of the rabbits' gut flora by oxytetracycline treatment significantly reduced the DAO inhibitory effect of furazolidone, suggesting that the gut flora may be involved in the transformation of furazolidone into an active DAO inhibitor.
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U2 - 10.1016/0742-8413(83)90159-7
DO - 10.1016/0742-8413(83)90159-7
M3 - Article
C2 - 6132752
AN - SCOPUS:0020682276
SN - 0306-4492
VL - 74
SP - 109
EP - 110
JO - Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology
JF - Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology
IS - 1
ER -