Abstract
A method for the preparation of [Â 3H]levetiracetam with a high specific activity of 98Ci/mmol (3.6TBq/mmol) is described. The radioligand proved to be highly useful for the labeling of specific levetiracetam binding sites in rat brain membrane preparations.
Original language | English |
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Pages (from-to) | 48-51 |
Number of pages | 4 |
Journal | Journal of Labelled Compounds and Radiopharmaceuticals |
Volume | 55 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 2012 |
Externally published | Yes |
Keywords
- SV2A protein
- epilepsy
- high specific activity
- levetiracetam
- tritium labeling
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Radiology Nuclear Medicine and imaging
- Drug Discovery
- Spectroscopy
- Organic Chemistry