Abstract
Rod-like CeO 2 nanoparticles (NPs) were produced by the quick precipitation approach and employed as a catalyzer to increase the chemiluminescence (CL) intensity of the luminol-O 2 reaction. The transmission electron microscopy (TEM) images of the CeO 2 NPs showed that rod-like particles with the length and diameter about 15 nm and 5 nm, respectively, were produced. Furthermore, pharmaceuticals including oxcarbazepine (OXP) and ascorbic acid (AA) showed an inhibitory effect against the CL intensity such that the more concentration of the pharmaceuticals, the less was the CL intensity. Therefore, the new CeO 2 NPs-luminol-O 2 CL reaction was developed to determine OXP and AA in the pharmaceutical formulations. It is the first CL method established for the quantification of OXP. The linear dynamic range of this method for OXP was from 6.0 × 10 -7 to 6.0 × 10 -5 mol L -1 and for AA from 1.0 × 10 -6 to 1.0 × 10 -4 mol L -1.
Original language | English |
---|---|
Pages (from-to) | 787-793 |
Number of pages | 7 |
Journal | Analytical Sciences |
Volume | 38 |
Issue number | 5 |
DOIs | |
Publication status | Published - Mar 17 2022 |
Keywords
- Ascorbic acid
- CeO nanoparticles
- Chemiluminescence
- Luminol
- Oxcarbazepine
- Nanoparticles
- Ascorbic Acid
- Luminescence
- Cerium
- Pharmaceutical Preparations
- Luminescent Measurements/methods
ASJC Scopus subject areas
- Analytical Chemistry