Synthesis of Mixed Arylalkyl Tertiary Phosphines via the Grignard Approach

Ashanul Haque*, Khalaf M. Alenezi, Hani El Moll, Muhammad S. Khan, Wai Yeung Wong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Trialkyl and triaryl phosphines are important classes of ligands in the field of catalysis and materials research. The wide usability of these low-valent phosphines has led to the design and development of new synthesis routes for a variety of phosphines. In the present work, we report the synthesis and characterization of some mixed arylalkyl tertiary phosphines via the Grignard approach. A new asymmetric phosphine is characterized extensively by multi-spectroscopic techniques. IR and UV–Vis spectra of some selected compounds are also compared and discussed. Density functional theory (DFT)-calculated results support the formation of the new compounds.

Original languageEnglish
Article number4253
JournalMolecules
Volume27
Issue number13
DOIs
Publication statusPublished - Jul 1 2022

Keywords

  • cross-coupling
  • Grignard reaction
  • organophosphorus chemistry
  • phosphines
  • trivalent phosphorus

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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