Abstract
A novel, ecofriendly, one pot solvent free method for the synthesis of 4-aryl-7,7-dimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2-one/thione-5-one derivatives is described which devoids the use of any organic solvents and auxiliaries. All the synthesized compounds were screened for their in vitro antibacterial activity against standard strains of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa.
Original language | English |
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Pages (from-to) | 816-819 |
Number of pages | 4 |
Journal | European Journal of Medicinal Chemistry |
Volume | 40 |
Issue number | 8 |
DOIs | |
Publication status | Published - Aug 2005 |
Keywords
- Antibacterial activity
- Microwave irradiation
- Quinazolines
- Solvent free
ASJC Scopus subject areas
- Molecular Medicine
- Organic Chemistry
- Drug Discovery
- Pharmaceutical Science