Abstract
The 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1.2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1,2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coti ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC 10231.
| Original language | English |
|---|---|
| Pages (from-to) | 1273-1275 |
| Number of pages | 3 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 37 |
| Issue number | 5 |
| Publication status | Published - 2000 |
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ASJC Scopus subject areas
- Organic Chemistry
Cite this
Synthesis and properties of some 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)quinoxalines. / Abdel-Jalil, R. J.; Al-Qawasmeh, R. A.; Voelter, W.; Heeg, P.; El-Abadelah, M. M.; Sabri, S. S.
In: Journal of Heterocyclic Chemistry, Vol. 37, No. 5, 2000, p. 1273-1275.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Synthesis and properties of some 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)quinoxalines
AU - Abdel-Jalil, R. J.
AU - Al-Qawasmeh, R. A.
AU - Voelter, W.
AU - Heeg, P.
AU - El-Abadelah, M. M.
AU - Sabri, S. S.
PY - 2000
Y1 - 2000
N2 - The 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1.2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1,2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coti ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC 10231.
AB - The 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1.2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1,2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coti ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC 10231.
UR - http://www.scopus.com/inward/record.url?scp=0033756483&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033756483&partnerID=8YFLogxK
M3 - Article
VL - 37
SP - 1273
EP - 1275
JO - Journal of Heterocyclic Chemistry
JF - Journal of Heterocyclic Chemistry
SN - 0022-152X
IS - 5
ER -