The 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1.2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1,2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coti ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC 10231.
|Number of pages||3|
|Journal||Journal of Heterocyclic Chemistry|
|Publication status||Published - 2000|
ASJC Scopus subject areas
- Organic Chemistry