Synthesis and properties of some 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)quinoxalines

R. J. Abdel-Jalil, R. A. Al-Qawasmeh, W. Voelter*, P. Heeg, M. M. El-Abadelah, S. S. Sabri

*Corresponding author for this work

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1.2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1,2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coti ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC 10231.

Original languageEnglish
Pages (from-to)1273-1275
Number of pages3
JournalJournal of Heterocyclic Chemistry
Volume37
Issue number5
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Organic Chemistry

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  • Cite this

    Abdel-Jalil, R. J., Al-Qawasmeh, R. A., Voelter, W., Heeg, P., El-Abadelah, M. M., & Sabri, S. S. (2000). Synthesis and properties of some 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)quinoxalines. Journal of Heterocyclic Chemistry, 37(5), 1273-1275.