Abstract
The 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1.2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1,2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coti ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC 10231.
| Original language | English |
|---|---|
| Pages (from-to) | 1273-1275 |
| Number of pages | 3 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 37 |
| Issue number | 5 |
| Publication status | Published - 2000 |
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ASJC Scopus subject areas
- Organic Chemistry
Cite this
Abdel-Jalil, R. J., Al-Qawasmeh, R. A., Voelter, W., Heeg, P., El-Abadelah, M. M., & Sabri, S. S. (2000). Synthesis and properties of some 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)quinoxalines. Journal of Heterocyclic Chemistry, 37(5), 1273-1275.