Synthesis and properties of some 2, 3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)quinoxalines

Raid J. Abdel-Jalil, Raed A. Al-Qawasmeh, Wolfgang Voelter, Peter Heeg, Mustafa M. El-Abadelah, Salim S. Sabri

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

The 2, 3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1.2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1, 2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coti ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC 10231.

Original languageEnglish
Pages (from-to)1273-1275
Number of pages3
JournalJournal of Heterocyclic Chemistry
Volume37
Issue number5
DOIs
Publication statusPublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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