Synthesis and properties of selected 4-substituted anhydro sugars

Raid J. Abdel-Jalil, Muhammad Saeed, Peter Heeg, Wolfgang Voelter

Research output: Contribution to journalArticle

Abstract

A new class of 4-deoxy-4-([4-substituted-1-piperazinyl], [4-morpholinyl] and [4-(perhydro1,4-thiazin-4-y])])-2,3-anhydrolyxopyranosides (3a-g and 6a-g) were synthesized from epoxy triflate moities 2 and 5 and 4-substituted piperazines, morpholines and perhydro-1,4-thiazines, respectively, to test their antibacterial activity. The characterized series of new compounds was tested in vitro against E. coli ATCC11229, S. aureus ATCC6538 and C. albicans SATCC10231.

Original languageEnglish
Pages (from-to)661-666
Number of pages6
JournalZeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
Volume55
Issue number7
Publication statusPublished - Jul 2000

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Morpholines
Piperazines
Thiazines
Sugars
Escherichia coli

Keywords

  • Anhydro sugars
  • Piperazine derivatives

ASJC Scopus subject areas

  • Inorganic Chemistry
  • Organic Chemistry

Cite this

Synthesis and properties of selected 4-substituted anhydro sugars. / Abdel-Jalil, Raid J.; Saeed, Muhammad; Heeg, Peter; Voelter, Wolfgang.

In: Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, Vol. 55, No. 7, 07.2000, p. 661-666.

Research output: Contribution to journalArticle

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