Synthesis and properties of selected 4-substituted anhydro sugars

Raid J. Abdel-Jalil, Muhammad Saeed, Peter Heeg, Wolfgang Voelter*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A new class of 4-deoxy-4-([4-substituted-1-piperazinyl], [4-morpholinyl] and [4-(perhydro1,4-thiazin-4-y])])-2,3-anhydrolyxopyranosides (3a-g and 6a-g) were synthesized from epoxy triflate moities 2 and 5 and 4-substituted piperazines, morpholines and perhydro-1,4-thiazines, respectively, to test their antibacterial activity. The characterized series of new compounds was tested in vitro against E. coli ATCC11229, S. aureus ATCC6538 and C. albicans SATCC10231.

Original languageEnglish
Pages (from-to)661-666
Number of pages6
JournalZeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
Volume55
Issue number7
DOIs
Publication statusPublished - Jul 2000
Externally publishedYes

Keywords

  • Anhydro sugars
  • Piperazine derivatives

ASJC Scopus subject areas

  • General Chemistry

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