Successful treatment of severe thrombocytopenia with romiplostim in a pregnant patient with systemic lupus erythematosus

J. K. Alkaabi, S. Alkindi, N. Al Riyami, F. Zia, L. M A Balla, S. M. Balla

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

We present a case of a pregnant woman at 27 weeks of gestation with systemic lupus erythematosus who developed severe thrombocytopenia presenting with melena, epistaxis, gum bleeding and frank hematuria. She was resistant to most treatment modalities, including steroids, intravenous immunoglobulins (IVIG), rituximab, IV cyclophosphamide and eltrombopag. She responded to romiplostim with normalization of her platelet count, which enabled her to be delivered safely at 34 weeks of gestation.

Original languageEnglish
Pages (from-to)1571-1574
Number of pages4
JournalLupus
Volume21
Issue number14
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Thrombocytopenia
Systemic Lupus Erythematosus
Melena
Pregnancy
Epistaxis
Intravenous Immunoglobulins
Gingiva
Hematuria
Platelet Count
Cyclophosphamide
Pregnant Women
Steroids
Hemorrhage
Therapeutics
romiplostim
eltrombopag
Rituximab

Keywords

  • Antiphospholipid syndrome
  • eltrombopag
  • Evans syndrome
  • rituximab
  • romiplostim
  • systemic lupus erythematosus
  • thrombocytopenia

ASJC Scopus subject areas

  • Rheumatology

Cite this

Successful treatment of severe thrombocytopenia with romiplostim in a pregnant patient with systemic lupus erythematosus. / Alkaabi, J. K.; Alkindi, S.; Riyami, N. Al; Zia, F.; Balla, L. M A; Balla, S. M.

In: Lupus, Vol. 21, No. 14, 12.2012, p. 1571-1574.

Research output: Contribution to journalArticle

Alkaabi, J. K. ; Alkindi, S. ; Riyami, N. Al ; Zia, F. ; Balla, L. M A ; Balla, S. M. / Successful treatment of severe thrombocytopenia with romiplostim in a pregnant patient with systemic lupus erythematosus. In: Lupus. 2012 ; Vol. 21, No. 14. pp. 1571-1574.
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