TY - JOUR
T1 - Stress associated with road transportation in desert sheep and goats, and the effect of pretreatment with xylazine or sodium betaine
AU - Ali, B. H.
AU - Al-Qarawi, A. A.
AU - Mousa, H. M.
N1 - Funding Information:
This work was supported by a grant from King Abul Aziz City of Science and Technology (Grant # LGP-7– 49). The technical help of Dr. O.H. Omer and Mr. E. El Bashir is acknowledged. Thanks to Professor G. Blunden for a gift of sodium betaine and the staff of the University Animal Farm for help with the animals.
PY - 2006/6
Y1 - 2006/6
N2 - The present work investigates some clinical, endocrinological, biochemical and haematological variables in desert sheep and goats stressed in the course of individual road transportation, and the influence thereon of pretreatment with an established anti-stressor drug, xylazine HCl, and a test compound, sodium betaine (trimethylglycine). Road transportation for 2 h resulted in variable and statistically insignificant increases in heart, pulse and respiratory rates in both control and experimental animals. Transportation stress significantly increased the concentrations of plasma cortisol, and glucose, and decreased that of magnesium. The endogenous thiocyanate concentration was unaffected. The stress also insignificantly decreased the haematocrit (PCV), and the number of lymphocytes, and increased the concentration of haemoglobin. Pretreatment of sheep and goats with xylazine at a single dose of 0.01 mg/kg by the intravenous route significantly ameliorated the effects induced by the stressful stimulus. The effects of pretreatment of the two species with sodium betaine (10 mg/kg) produced variable and insignificant effects.
AB - The present work investigates some clinical, endocrinological, biochemical and haematological variables in desert sheep and goats stressed in the course of individual road transportation, and the influence thereon of pretreatment with an established anti-stressor drug, xylazine HCl, and a test compound, sodium betaine (trimethylglycine). Road transportation for 2 h resulted in variable and statistically insignificant increases in heart, pulse and respiratory rates in both control and experimental animals. Transportation stress significantly increased the concentrations of plasma cortisol, and glucose, and decreased that of magnesium. The endogenous thiocyanate concentration was unaffected. The stress also insignificantly decreased the haematocrit (PCV), and the number of lymphocytes, and increased the concentration of haemoglobin. Pretreatment of sheep and goats with xylazine at a single dose of 0.01 mg/kg by the intravenous route significantly ameliorated the effects induced by the stressful stimulus. The effects of pretreatment of the two species with sodium betaine (10 mg/kg) produced variable and insignificant effects.
KW - Betaine
KW - Goats
KW - Sheep
KW - Stress
KW - Transportation
KW - Xylazine
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U2 - 10.1016/j.rvsc.2005.07.012
DO - 10.1016/j.rvsc.2005.07.012
M3 - Article
C2 - 16181650
AN - SCOPUS:32044452935
SN - 0034-5288
VL - 80
SP - 343
EP - 348
JO - Research in Veterinary Science
JF - Research in Veterinary Science
IS - 3
ER -