Spontaneously resolving macular cyst in an infant

Anuradha Ganesh, Misha Khalighi, Kristin Hammersmith, Alex Levin

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The purpose of this study is to describe transient macular cysts in an infant and correlate their occurrence with normal development events. A newborn Caucasian girl presented with a protruding corneal mass in her left eye at birth. She underwent a complete ophthalmic examination. A keratinized staphylomatous malformation involving the entire cornea and precluding further visualization of the anterior and posterior segment was observed in the left eye. Spectral domain optical coherence tomography (SD-OCT) of the right eye performed when the child was approximately 6-week-old had revealed an unexpected finding of macular cysts involving the inner nuclear and outer retinal layers. Corneal transplant in the left eye was performed a month later. Ocular examination under anesthesia just prior to surgery revealed normal intraocular pressure, anterior segment and retina in the right eye. SD-OCT was normal in both eyes and showed complete resolution of the cysts in the right eye. The patient had not been on any medications at that time. Although clinical retinal examination might be unremarkable, SD-OCT may reveal cystic spaces in the macula. In the absence of conditions known to be associated with macular edema, transient macular cysts may arise due to a developmental incompetence of the blood-retinal barrier or may represent transient spaces created during normal migration of retinal cells. Further study is warranted to delineate the entity of transient macular cysts in infancy. Copyright:

Original languageEnglish
Pages (from-to)203-205
Number of pages3
JournalOman Journal of Ophthalmology
Volume6
Issue number3
DOIs
Publication statusPublished - Sep 2013

Fingerprint

Cysts
Optical Coherence Tomography
Blood-Retinal Barrier
Macular Edema
Intraocular Pressure
Cornea
Cell Movement
Retina
Anesthesia
Parturition
Newborn Infant
Transplants

Keywords

  • Blood-retinal barrier
  • developmental
  • infant
  • macular cyst
  • optical coherence tomography
  • retina
  • transient

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Spontaneously resolving macular cyst in an infant. / Ganesh, Anuradha; Khalighi, Misha; Hammersmith, Kristin; Levin, Alex.

In: Oman Journal of Ophthalmology, Vol. 6, No. 3, 09.2013, p. 203-205.

Research output: Contribution to journalArticle

Ganesh, Anuradha ; Khalighi, Misha ; Hammersmith, Kristin ; Levin, Alex. / Spontaneously resolving macular cyst in an infant. In: Oman Journal of Ophthalmology. 2013 ; Vol. 6, No. 3. pp. 203-205.
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