TY - JOUR
T1 - Spectrum of external catheter-related infections in children with acute leukemia-Single-center experience
AU - Zachariah, M.
AU - Al-Yazidi, L.
AU - Bashir, W.
AU - Al Rawas, A. H.
AU - Wali, Y.
AU - Pathare, A. V.
PY - 2014/2
Y1 - 2014/2
N2 - Background: External catheters (ECs) are commonly used in children who are receiving treatment for acute leukemia. Aims: To study the spectrum of microorganisms and to compare the rates of infection. Methods: A total of 42 ECs were inserted, including 28 Port-A-Caths, 11 CVC lines and 3 Hickman lines. Single ECs were required for 19 patients (45.2%), whereas 2, 3 and 4 ECs were required in 8, 1 and 1 patients, respectively. Results: Overall, 37 culture-documented infections were present in 18 (62%) patients who had ECs. Gram-positive microorganisms were identified in 20 cases, Gram-negative microorganisms in 14 cases and fungal infections in 3 cases. Of the 42 devices implanted, 10 out of 28 Port-A-Caths (35.7%), 2 out of 3 Hickman catheters (66.7%) and 9 out of 11 central venous catheters (81.8%) required removal due to infection. The average length of working life for the ports was 330.6 days (range: 40-1043 days). The median rate of complications due to infection was 2.84 infections per 1000 catheter days (interquartile range: -1.55 to 5.8), and the number of infections was correlated with the number of ports (Pearson's r= 0.51; p
AB - Background: External catheters (ECs) are commonly used in children who are receiving treatment for acute leukemia. Aims: To study the spectrum of microorganisms and to compare the rates of infection. Methods: A total of 42 ECs were inserted, including 28 Port-A-Caths, 11 CVC lines and 3 Hickman lines. Single ECs were required for 19 patients (45.2%), whereas 2, 3 and 4 ECs were required in 8, 1 and 1 patients, respectively. Results: Overall, 37 culture-documented infections were present in 18 (62%) patients who had ECs. Gram-positive microorganisms were identified in 20 cases, Gram-negative microorganisms in 14 cases and fungal infections in 3 cases. Of the 42 devices implanted, 10 out of 28 Port-A-Caths (35.7%), 2 out of 3 Hickman catheters (66.7%) and 9 out of 11 central venous catheters (81.8%) required removal due to infection. The average length of working life for the ports was 330.6 days (range: 40-1043 days). The median rate of complications due to infection was 2.84 infections per 1000 catheter days (interquartile range: -1.55 to 5.8), and the number of infections was correlated with the number of ports (Pearson's r= 0.51; p
KW - Acute leukemia
KW - Catheter
KW - Culture
KW - Hickman
KW - Infection
KW - Port-A-Cath
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U2 - 10.1016/j.jiph.2013.06.005
DO - 10.1016/j.jiph.2013.06.005
M3 - Article
C2 - 23999354
AN - SCOPUS:84892871123
VL - 7
SP - 38
EP - 43
JO - Journal of Infection and Public Health
JF - Journal of Infection and Public Health
SN - 1876-0341
IS - 1
ER -