Seizure heralding functional recovery in a patient with apallic syndrome

A case report with retrospective-prospective observation

Samir Al-Adawi, David T. Burke, Sara E. Mastronardi

Research output: Contribution to journalArticle

Abstract

Background: It has been suggested that there exists a close relationship between seizure discharges and functional recovery from brain injury, and that paroxysmal bombardment in late seizures may herald functional recovery or may "kick-start" recovery. Case report: We report the case of a 52-year-old patient who, following a subarachnoid hemorrhage and multiple surgeries, experienced discernible apallic syndrome of long duration. His hospitalization is well documented. The patient underwent protracted, intense rehabilitation, but he remained in this prolonged state of loss of consciousness and behavioral passivity until he experienced a series of periodic seizures. Widespread improvement in his cognitive and functional abilities coincided closely with the seizure activity. The literature on this topic is reviewed. Conclusion: This case confirms the close relationship between seizure discharges and functional recovery reported in preclinical literature.

Original languageEnglish
Pages (from-to)776-780
Number of pages5
JournalEpilepsy and Behavior
Volume8
Issue number4
DOIs
Publication statusPublished - Jun 2006

Fingerprint

Seizures
Observation
Unconsciousness
Subarachnoid Hemorrhage
Brain Injuries
Hospitalization
Rehabilitation

Keywords

  • Apallic syndrome
  • Case report
  • Functional recovery
  • Seizure
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology

Cite this

Seizure heralding functional recovery in a patient with apallic syndrome : A case report with retrospective-prospective observation. / Al-Adawi, Samir; Burke, David T.; Mastronardi, Sara E.

In: Epilepsy and Behavior, Vol. 8, No. 4, 06.2006, p. 776-780.

Research output: Contribution to journalArticle

@article{5d80b96a4b294d349a8dd6d3d2b1841a,
title = "Seizure heralding functional recovery in a patient with apallic syndrome: A case report with retrospective-prospective observation",
abstract = "Background: It has been suggested that there exists a close relationship between seizure discharges and functional recovery from brain injury, and that paroxysmal bombardment in late seizures may herald functional recovery or may {"}kick-start{"} recovery. Case report: We report the case of a 52-year-old patient who, following a subarachnoid hemorrhage and multiple surgeries, experienced discernible apallic syndrome of long duration. His hospitalization is well documented. The patient underwent protracted, intense rehabilitation, but he remained in this prolonged state of loss of consciousness and behavioral passivity until he experienced a series of periodic seizures. Widespread improvement in his cognitive and functional abilities coincided closely with the seizure activity. The literature on this topic is reviewed. Conclusion: This case confirms the close relationship between seizure discharges and functional recovery reported in preclinical literature.",
keywords = "Apallic syndrome, Case report, Functional recovery, Seizure, Stroke",
author = "Samir Al-Adawi and Burke, {David T.} and Mastronardi, {Sara E.}",
year = "2006",
month = "6",
doi = "10.1016/j.yebeh.2006.03.001",
language = "English",
volume = "8",
pages = "776--780",
journal = "Epilepsy and Behavior",
issn = "1525-5050",
publisher = "Academic Press Inc.",
number = "4",

}

TY - JOUR

T1 - Seizure heralding functional recovery in a patient with apallic syndrome

T2 - A case report with retrospective-prospective observation

AU - Al-Adawi, Samir

AU - Burke, David T.

AU - Mastronardi, Sara E.

PY - 2006/6

Y1 - 2006/6

N2 - Background: It has been suggested that there exists a close relationship between seizure discharges and functional recovery from brain injury, and that paroxysmal bombardment in late seizures may herald functional recovery or may "kick-start" recovery. Case report: We report the case of a 52-year-old patient who, following a subarachnoid hemorrhage and multiple surgeries, experienced discernible apallic syndrome of long duration. His hospitalization is well documented. The patient underwent protracted, intense rehabilitation, but he remained in this prolonged state of loss of consciousness and behavioral passivity until he experienced a series of periodic seizures. Widespread improvement in his cognitive and functional abilities coincided closely with the seizure activity. The literature on this topic is reviewed. Conclusion: This case confirms the close relationship between seizure discharges and functional recovery reported in preclinical literature.

AB - Background: It has been suggested that there exists a close relationship between seizure discharges and functional recovery from brain injury, and that paroxysmal bombardment in late seizures may herald functional recovery or may "kick-start" recovery. Case report: We report the case of a 52-year-old patient who, following a subarachnoid hemorrhage and multiple surgeries, experienced discernible apallic syndrome of long duration. His hospitalization is well documented. The patient underwent protracted, intense rehabilitation, but he remained in this prolonged state of loss of consciousness and behavioral passivity until he experienced a series of periodic seizures. Widespread improvement in his cognitive and functional abilities coincided closely with the seizure activity. The literature on this topic is reviewed. Conclusion: This case confirms the close relationship between seizure discharges and functional recovery reported in preclinical literature.

KW - Apallic syndrome

KW - Case report

KW - Functional recovery

KW - Seizure

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=33646517059&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646517059&partnerID=8YFLogxK

U2 - 10.1016/j.yebeh.2006.03.001

DO - 10.1016/j.yebeh.2006.03.001

M3 - Article

VL - 8

SP - 776

EP - 780

JO - Epilepsy and Behavior

JF - Epilepsy and Behavior

SN - 1525-5050

IS - 4

ER -