TY - JOUR
T1 - Secondary intracranial hypertension in aplastic anemia
T2 - A case report and review of current concepts
AU - Al Musalami, Adil
AU - Elmanzalawy, Alaa
AU - Wali, Yasser
AU - Ganesh, Anuradha
N1 - Publisher Copyright:
© 2021 Wolters Kluwer Medknow Publications. All rights reserved.
PY - 2021/9/1
Y1 - 2021/9/1
N2 - Intracranial hypertension (IH) when detected mandates prompt and appropriate therapy to avoid permanent visual impairment. We report a 7-year-old boy who presented to the emergency services with purpuric rashes and bruises. Peripheral blood smear and bone marrow aspiration confirmed the diagnosis of aplastic anemia. During admission, the child developed headache, nausea, vomiting, and diplopia. Ophthalmic examination revealed intermittent esotropia and bilateral papilledema. The findings on neuroimaging and lumbar puncture led to the diagnosis of secondary IH (SIH). The intracranial pressure normalized on treatment with oral acetazolamide, oral furosemide, and intravenous dexamethasone.
AB - Intracranial hypertension (IH) when detected mandates prompt and appropriate therapy to avoid permanent visual impairment. We report a 7-year-old boy who presented to the emergency services with purpuric rashes and bruises. Peripheral blood smear and bone marrow aspiration confirmed the diagnosis of aplastic anemia. During admission, the child developed headache, nausea, vomiting, and diplopia. Ophthalmic examination revealed intermittent esotropia and bilateral papilledema. The findings on neuroimaging and lumbar puncture led to the diagnosis of secondary IH (SIH). The intracranial pressure normalized on treatment with oral acetazolamide, oral furosemide, and intravenous dexamethasone.
KW - Aplastic anemia
KW - idiopathic intracranial hypertension
KW - intracranial hypertension
KW - papilledema
KW - secondary intracranial hypertension
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U2 - 10.4103/ojo.ojo_79_21
DO - 10.4103/ojo.ojo_79_21
M3 - Review article
C2 - 34880583
AN - SCOPUS:85118751366
SN - 0974-620X
VL - 14
SP - 190
EP - 195
JO - Oman Journal of Ophthalmology
JF - Oman Journal of Ophthalmology
IS - 3
ER -