Schistosoma mansoni diagnostic antigens (Sm 31/12): A sero-epidemiological study in the sudan

A. Ruppel, M. A. Idris, S. M. Sulaiman, A. M H Hilali

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25 Citations (Scopus)

Abstract

A cross-sectional study was performed in a Sudanese village endemic for intestinal schistosomiasis and not located in a control area. Immunological and parasitological diagnosis were compared in 156 individuals. Sera were tested with defined diagnostic Schistosoma mansoni antigens (Sm 31/32, i.e. hemoglobinase and cathepsin), and repeated stool examinations were performed. In immunoblots, 98% of the egg excretors were correctly identified. On the other hand, 75% of the parasitologically negative individuals had anti-Sm 31/32 antibodies. Cross-reactivity of these antigens with other parasites was excluded earlier, and the patients had not received previous chemotherapy. It is concluded that the sensitivity of these defined antigens to detect immunologically infections with S. mansoni compares favourably with stool examinations.

Original languageEnglish
Pages (from-to)127-130
Number of pages4
JournalTropical Medicine and Parasitology
Volume41
Issue number2
Publication statusPublished - 1990

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Sudan
Schistosoma mansoni
Epidemiologic Studies
Schistosomiasis mansoni
Antigens
Cathepsins
Immunologic Tests
Ovum
Parasites
Cross-Sectional Studies
Drug Therapy
Antibodies
Serum

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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Schistosoma mansoni diagnostic antigens (Sm 31/12) : A sero-epidemiological study in the sudan. / Ruppel, A.; Idris, M. A.; Sulaiman, S. M.; Hilali, A. M H.

In: Tropical Medicine and Parasitology, Vol. 41, No. 2, 1990, p. 127-130.

Research output: Contribution to journalArticle

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