TY - JOUR
T1 - Risk factors for type 1 diabetes mellitus in children live in karbala province-iraq.
AU - Abdaljabbar, Haider Nadhim
AU - Al-Rubae, Alaa Mohaisen
AU - Faraj, Safa A.
AU - Alsaffar, Hussain
AU - Taher, Taqi Mohammed Jwad
N1 - Publisher Copyright:
© 2021, Scientific Publishers of India. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Background: The most important autoimmune disease which affects children is Type 1 Diabetes Mellitus (T1DM). The main risk factor for this chronic condition is genetic that contributed to loci within the HLA complex. Even, the environmental issues triggering the disease are still unclear so this study aimed to identify the most important risk factors related to type 1 diabetes mellitus among children and adolescents. Methods: This is a descriptive cross-sectional study conducted among 50 confirmed diabetic children and adolescents visiting AL-Hussainy hospital in Karbala. Time of data collection continuous for two month i.e. July and August 2019. After consenting for voluntary participation in the study, parents were answering a special questionnaire containing demographic and risk factors data. Results: The age range of participate diabetic children was (18 months-17 years), around 70% of patients have never had a family history of diabetes and only 32% mentioned having thyroid diseases among their relatives. Analysis of the related maternal risk factors was showing the majority (84%) was drinking tea during pregnancy; no one had a smoking history. Only 6% diagnosed with gestational diabetes and 3% were treated with insulin. Regarding factors associated with the neonatal period, all children were delivered in the hospitals and 68% of these deliveries were normal and more than half 54% had no disease during their neonatal life. Most of the participant children (80%) continued their breastfeeding for more than 6 months. Conclusion: there are a lot of environmental risk factors related to pregnancy, neonatal period, and early childhood widely distributed among patients with type 1 DM and may have their role in causing diabetes among those patients.
AB - Background: The most important autoimmune disease which affects children is Type 1 Diabetes Mellitus (T1DM). The main risk factor for this chronic condition is genetic that contributed to loci within the HLA complex. Even, the environmental issues triggering the disease are still unclear so this study aimed to identify the most important risk factors related to type 1 diabetes mellitus among children and adolescents. Methods: This is a descriptive cross-sectional study conducted among 50 confirmed diabetic children and adolescents visiting AL-Hussainy hospital in Karbala. Time of data collection continuous for two month i.e. July and August 2019. After consenting for voluntary participation in the study, parents were answering a special questionnaire containing demographic and risk factors data. Results: The age range of participate diabetic children was (18 months-17 years), around 70% of patients have never had a family history of diabetes and only 32% mentioned having thyroid diseases among their relatives. Analysis of the related maternal risk factors was showing the majority (84%) was drinking tea during pregnancy; no one had a smoking history. Only 6% diagnosed with gestational diabetes and 3% were treated with insulin. Regarding factors associated with the neonatal period, all children were delivered in the hospitals and 68% of these deliveries were normal and more than half 54% had no disease during their neonatal life. Most of the participant children (80%) continued their breastfeeding for more than 6 months. Conclusion: there are a lot of environmental risk factors related to pregnancy, neonatal period, and early childhood widely distributed among patients with type 1 DM and may have their role in causing diabetes among those patients.
KW - Autoimmune disease
KW - Children
KW - Risk factors
KW - Type 1 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=85112697270&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85112697270&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85112697270
SN - 0971-9032
VL - 25
SP - 663
EP - 668
JO - Current Pediatric Research
JF - Current Pediatric Research
IS - 7
ER -