TY - JOUR
T1 - Revised workflow practices in the management of acute invasive fungal sinusitis during the COVID-19 pandemic
AU - Kurien, Regi
AU - Varghese, Lalee
AU - Cherian, Lisa Mary
AU - Sundaresan, Rajan
AU - John, Mary
AU - Mammen, Manju Deena
AU - Inja, Ranjeetha Racheal
AU - Manesh, Abi
AU - Paul, Hema
AU - Gurijala, Phaneendra Rao
AU - Michael, Joy Sarojini
AU - Thomas, Meera
AU - Abhilash, Kundavaram Paul Prabhakar
AU - Varghese, Ajoy Mathew
AU - Rupa, Vedantam
N1 - Publisher Copyright:
© 2022 Cambridge University Press. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Objective: To document changes in evaluation protocols for acute invasive fungal sinusitis (AIFS) during the COVID-19 pandemic and to analyse concordance between clinical and histopathological diagnosis based on new practice guidelines. Methods: Protocols for patient evaluation with suspected AIFS both prior and during the COVID-19 period are described. Retrospective analysis of patients with suspected AIFS from May 1st to June 30th 2021 and the concordance between clinical and final diagnosis was done. Results: Among 171 patients with high clinical suspicion, 160 (93.6%) correlated with the final histopathological diagnosis of invasive fungal sinusitis, providing a 100% sensitivity, positive predictive value of 93.6% and a negative predictive value of 100%. Conclusion: Our study highlights a valuable screening tool with good accuracy involving emphasis on red flag signs in high-risk populations. This could be valuable in situations demanding avoidance of aerosol generating procedures and in resource limited settings facilitating early referral to higher centres.
AB - Objective: To document changes in evaluation protocols for acute invasive fungal sinusitis (AIFS) during the COVID-19 pandemic and to analyse concordance between clinical and histopathological diagnosis based on new practice guidelines. Methods: Protocols for patient evaluation with suspected AIFS both prior and during the COVID-19 period are described. Retrospective analysis of patients with suspected AIFS from May 1st to June 30th 2021 and the concordance between clinical and final diagnosis was done. Results: Among 171 patients with high clinical suspicion, 160 (93.6%) correlated with the final histopathological diagnosis of invasive fungal sinusitis, providing a 100% sensitivity, positive predictive value of 93.6% and a negative predictive value of 100%. Conclusion: Our study highlights a valuable screening tool with good accuracy involving emphasis on red flag signs in high-risk populations. This could be valuable in situations demanding avoidance of aerosol generating procedures and in resource limited settings facilitating early referral to higher centres.
KW - COVID-19
KW - mucormycosis
KW - paranasal sinuses
KW - sinusitis
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U2 - 10.1017/S0022215122001888
DO - 10.1017/S0022215122001888
M3 - Article
C2 - 35971740
AN - SCOPUS:85136585431
SN - 0022-2151
JO - Journal of Laryngology and Otology
JF - Journal of Laryngology and Otology
ER -