Reactivity of Schistosoma japonicum and S. Mansoni antigen preparations in indirect haemagglutination (IHA) with sera of patients with homologous and heterologous schistosomiasis

M. Gui; M. A. Idris; Y. E. Shi; A. Muhling; A. Ruppel

Reactivity of Schistosoma japonicum and S. Mansoni antigen preparations in indirect haemagglutination (IHA) with sera of patients with homologous and heterologous schistosomiasis

M. Gui, M. A. Idris, Y. E. Shi, A. Muhling, A. Ruppel^*

^*Corresponding author for this work

Microbiology & Immunology

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

Sera of patients infected with Schistosoma japonicum, S. mansoni or S. haematobium were tested in an indirect haemagglutination assay (IHA) using soluble S. japonicum egg antigen (SjSEA) and soluble S. mansoni adult antigen prepared either from a Puerto Rican strain (SmAWA) or an Egyptian strain (SmBW; Cellognost(®)-Schistosomiasis Kit). Reactions were best, in terms of titres and sensitivity, in homologous systems. Heterologous systems were less reliable, particularly those using sera from urinary schistosomiasis patients. It is suggested that IHA is a suitable test to detect Schistosoma infections, especially when homologous systems are used.

Original language	English
Pages (from-to)	599-604
Number of pages	6
Journal	Annals of Tropical Medicine and Parasitology
Volume	85
Issue number	6
Publication status	Published - 1991

ASJC Scopus subject areas

Immunology
Parasitology
Infectious Diseases

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Reactivity of Schistosoma japonicum and S. Mansoni antigen preparations in indirect haemagglutination (IHA) with sera of patients with homologous and heterologous schistosomiasis. / Gui, M.; Idris, M. A.; Shi, Y. E.; Muhling, A.; Ruppel, A.

In: Annals of Tropical Medicine and Parasitology, Vol. 85, No. 6, 1991, p. 599-604.

Research output: Contribution to journal › Article › peer-review

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abstract = "Sera of patients infected with Schistosoma japonicum, S. mansoni or S. haematobium were tested in an indirect haemagglutination assay (IHA) using soluble S. japonicum egg antigen (SjSEA) and soluble S. mansoni adult antigen prepared either from a Puerto Rican strain (SmAWA) or an Egyptian strain (SmBW; Cellognost({\textregistered})-Schistosomiasis Kit). Reactions were best, in terms of titres and sensitivity, in homologous systems. Heterologous systems were less reliable, particularly those using sera from urinary schistosomiasis patients. It is suggested that IHA is a suitable test to detect Schistosoma infections, especially when homologous systems are used.",

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AU - Shi, Y. E.

AU - Muhling, A.

AU - Ruppel, A.

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AB - Sera of patients infected with Schistosoma japonicum, S. mansoni or S. haematobium were tested in an indirect haemagglutination assay (IHA) using soluble S. japonicum egg antigen (SjSEA) and soluble S. mansoni adult antigen prepared either from a Puerto Rican strain (SmAWA) or an Egyptian strain (SmBW; Cellognost(®)-Schistosomiasis Kit). Reactions were best, in terms of titres and sensitivity, in homologous systems. Heterologous systems were less reliable, particularly those using sera from urinary schistosomiasis patients. It is suggested that IHA is a suitable test to detect Schistosoma infections, especially when homologous systems are used.

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Reactivity of Schistosoma japonicum and S. Mansoni antigen preparations in indirect haemagglutination (IHA) with sera of patients with homologous and heterologous schistosomiasis

Abstract

ASJC Scopus subject areas

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