Rapid and efficient microwave-assisted copper(0)-catalyzed ullmann coupling reaction

General access to anilinoanthraquinone derivatives

Younis Baqi, Christa E. Muller

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Figure presented The synthesis of anilinoanthraquinones 3a-z was achieved by a new, Cu(0)-catalyzed, microwave-assisted Ullmann coupling reaction of bromaminic acid (1) with aniline derivatives 2a-z in phosphate buffer. Good to excellent isolated yields were obtained within only 2-20 min at 80-120 °C and 40-100 W. The new procedure provides the first general access to anilinoanthraquinones, furnishing a number of previously inaccessible compounds. It is superior to classical methods in all aspects, including yields, reaction time, and versatility.

Original languageEnglish
Pages (from-to)1271-1274
Number of pages4
JournalOrganic Letters
Volume9
Issue number7
DOIs
Publication statusPublished - Mar 29 2007

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Microwaves
Copper
Buffers
Phosphates
Derivatives
microwaves
copper
versatility
aniline
reaction time
phosphates
buffers
acids
synthesis
bromamine acid

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Rapid and efficient microwave-assisted copper(0)-catalyzed ullmann coupling reaction : General access to anilinoanthraquinone derivatives. / Baqi, Younis; Muller, Christa E.

In: Organic Letters, Vol. 9, No. 7, 29.03.2007, p. 1271-1274.

Research output: Contribution to journalArticle

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