Proteomics: Concepts and applications in human medicine

Safa Al-Amrani, Zaaima Al-Jabri, Adhari Al-Zaabi, Jalila Alshekaili, Murtadha Al-Khabori

Research output: Contribution to journalReview articlepeer-review

Abstract

Proteomics is the complete evaluation of the function and structure of proteins to understand an organism's nature. Mass spectrometry is an essential tool that is used for profiling proteins in the cell. However, biomarker discovery remains the major challenge of proteomics because of their complexity and dynamicity. Therefore, combining the proteomics approach with genomics and bioinformatics will provide an understanding of the information of biological systems and their disease alteration. However, most studies have investigated a small part of the proteins in the blood. This review highlights the types of proteomics, the available proteomic techniques, and their applications in different research fields.

Original languageEnglish
Pages (from-to)57-69
Number of pages13
JournalWorld Journal of Biological Chemistry
Volume12
Issue number5
DOIs
Publication statusPublished - Sep 27 2021

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