Primary signet ring cell carcinoma of gall bladder: Report of an extremely rare histological type of primary gall bladder carcinoma

Zubair Ahmad, Asim Qureshi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Signet ring cell carcinoma is an extremely rare type of gall bladder carcinoma composed overwhelmingly (90%) of signet ring cells. It is necessary to exclude a gastric or colonic signet ring cell carcinoma secondarily involving the gall bladder. The primary aim of this case report is to describe the histopathological aspects of this tumour. Primary signet ring cell carcinoma of gall bladder shows dysplastic surface gall bladder epithelium with infiltration of gall bladder wall. It is also necessary to exclude benign signet ring change, which sometimes occurs in the gall bladder. However, it is always confined to the mucosa and does not infiltrate the wall. This case showed grossly diffuse thickening of the gall bladder wall and dysplastic surface epithelium of the gall bladder on histology, with sheets of signet ring cells infiltrating full thickness of the wall. It is also necessary to exclude benign signet ring cell change, which sometimes occurs in the gall bladder. However it is always confined to the mucosa and does not infiltrate the wall.

Original languageEnglish
JournalBMJ Case Reports
DOIs
Publication statusPublished - Sep 7 2010

Fingerprint

Signet Ring Cell Carcinoma
Urinary Bladder
Carcinoma
Mucous Membrane
Epithelium
Stomach
Histology

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{4102e7b86e894512afcee80cec204ab1,
title = "Primary signet ring cell carcinoma of gall bladder: Report of an extremely rare histological type of primary gall bladder carcinoma",
abstract = "Signet ring cell carcinoma is an extremely rare type of gall bladder carcinoma composed overwhelmingly (90{\%}) of signet ring cells. It is necessary to exclude a gastric or colonic signet ring cell carcinoma secondarily involving the gall bladder. The primary aim of this case report is to describe the histopathological aspects of this tumour. Primary signet ring cell carcinoma of gall bladder shows dysplastic surface gall bladder epithelium with infiltration of gall bladder wall. It is also necessary to exclude benign signet ring change, which sometimes occurs in the gall bladder. However, it is always confined to the mucosa and does not infiltrate the wall. This case showed grossly diffuse thickening of the gall bladder wall and dysplastic surface epithelium of the gall bladder on histology, with sheets of signet ring cells infiltrating full thickness of the wall. It is also necessary to exclude benign signet ring cell change, which sometimes occurs in the gall bladder. However it is always confined to the mucosa and does not infiltrate the wall.",
author = "Zubair Ahmad and Asim Qureshi",
year = "2010",
month = "9",
day = "7",
doi = "10.1136/bcr.04.2009.1782",
language = "English",
journal = "BMJ Case Reports",
issn = "1757-790X",
publisher = "BMJ Publishing Group",

}

TY - JOUR

T1 - Primary signet ring cell carcinoma of gall bladder

T2 - Report of an extremely rare histological type of primary gall bladder carcinoma

AU - Ahmad, Zubair

AU - Qureshi, Asim

PY - 2010/9/7

Y1 - 2010/9/7

N2 - Signet ring cell carcinoma is an extremely rare type of gall bladder carcinoma composed overwhelmingly (90%) of signet ring cells. It is necessary to exclude a gastric or colonic signet ring cell carcinoma secondarily involving the gall bladder. The primary aim of this case report is to describe the histopathological aspects of this tumour. Primary signet ring cell carcinoma of gall bladder shows dysplastic surface gall bladder epithelium with infiltration of gall bladder wall. It is also necessary to exclude benign signet ring change, which sometimes occurs in the gall bladder. However, it is always confined to the mucosa and does not infiltrate the wall. This case showed grossly diffuse thickening of the gall bladder wall and dysplastic surface epithelium of the gall bladder on histology, with sheets of signet ring cells infiltrating full thickness of the wall. It is also necessary to exclude benign signet ring cell change, which sometimes occurs in the gall bladder. However it is always confined to the mucosa and does not infiltrate the wall.

AB - Signet ring cell carcinoma is an extremely rare type of gall bladder carcinoma composed overwhelmingly (90%) of signet ring cells. It is necessary to exclude a gastric or colonic signet ring cell carcinoma secondarily involving the gall bladder. The primary aim of this case report is to describe the histopathological aspects of this tumour. Primary signet ring cell carcinoma of gall bladder shows dysplastic surface gall bladder epithelium with infiltration of gall bladder wall. It is also necessary to exclude benign signet ring change, which sometimes occurs in the gall bladder. However, it is always confined to the mucosa and does not infiltrate the wall. This case showed grossly diffuse thickening of the gall bladder wall and dysplastic surface epithelium of the gall bladder on histology, with sheets of signet ring cells infiltrating full thickness of the wall. It is also necessary to exclude benign signet ring cell change, which sometimes occurs in the gall bladder. However it is always confined to the mucosa and does not infiltrate the wall.

UR - http://www.scopus.com/inward/record.url?scp=84897883226&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897883226&partnerID=8YFLogxK

U2 - 10.1136/bcr.04.2009.1782

DO - 10.1136/bcr.04.2009.1782

M3 - Article

C2 - 22778190

AN - SCOPUS:84897883226

JO - BMJ Case Reports

JF - BMJ Case Reports

SN - 1757-790X

ER -