Prevalence of methicillin resistant Staphylococcus aureus [MRSA] colonization or carriage among health-care workers

Nirmal A. Pathare, Harshini Asogan, Sara Tejani, Gaitha Al Mahruqi, Salma Al Fakhri, Roshna Zafarulla, Anil V. Pathare

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

In Oman, the prevalence of health care associated methicillin resistant Staphylococcus aureus [HA-MRSA] is unknown. Therefore, to estimate the prevalence of HA-MRSA, we collected nasal swabs and swabs from cell phones on sterile polyester swabs and immediately inoculated on the mannitol salt agar containing oxacillin from medical students and hospital health care providers. Antibiotic susceptibility testing of the isolates was then performed using the Kirby Bauer's disc diffusion method. Additionally, a brief survey questionnaire was used to acquire demographic data. Amongst the 311 participants enrolled, nasal colonization with HA-MRSA was found in 47 individuals (15.1%, 95% confidence interval [CI] = 11.1%, 19.1%). HA-MRSA was also isolated from the cell phone surfaces in 28 participants (9.0%, 95% CI = 8.6%, 9.3%). 5 participants (1.6%) showed positive results both from their nasal swabs and from their cell phones. Antibiotic resistance to erythromycin [48%] and clindamycin [29%] was relatively high. 9.3% HA-MRSA isolates were vancomycin resistant [6.6% nasal carriage]. There was no statistically significant correlation between HA-MRSA isolates and the demographic characteristics or the risk factors namely gender, underlying co-morbidities like diabetes, hypertension, skin/soft tissue infections, skin ulcers/wounds, recent exposure to antibiotics, or hospital visits (p >. 0.05, Chi-square test).

Original languageEnglish
JournalJournal of Infection and Public Health
DOIs
Publication statusAccepted/In press - Aug 4 2015

Fingerprint

Methicillin-Resistant Staphylococcus aureus
Delivery of Health Care
Nose
Cell Phones
Disk Diffusion Antimicrobial Tests
Demography
Confidence Intervals
Oman
Skin Ulcer
Anti-Bacterial Agents
Oxacillin
Soft Tissue Infections
Polyesters
Clindamycin
Mannitol
Erythromycin
Chi-Square Distribution
Vancomycin
Microbial Drug Resistance
Medical Students

Keywords

  • HA-MRSA
  • Methicillin
  • Nasal
  • Oxacillin
  • Prevalence
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Infectious Diseases
  • Public Health, Environmental and Occupational Health

Cite this

Prevalence of methicillin resistant Staphylococcus aureus [MRSA] colonization or carriage among health-care workers. / Pathare, Nirmal A.; Asogan, Harshini; Tejani, Sara; Al Mahruqi, Gaitha; Al Fakhri, Salma; Zafarulla, Roshna; Pathare, Anil V.

In: Journal of Infection and Public Health, 04.08.2015.

Research output: Contribution to journalArticle

Pathare, Nirmal A. ; Asogan, Harshini ; Tejani, Sara ; Al Mahruqi, Gaitha ; Al Fakhri, Salma ; Zafarulla, Roshna ; Pathare, Anil V. / Prevalence of methicillin resistant Staphylococcus aureus [MRSA] colonization or carriage among health-care workers. In: Journal of Infection and Public Health. 2015.
@article{0a8aab3558bc40c09311ad15cfc90aa8,
title = "Prevalence of methicillin resistant Staphylococcus aureus [MRSA] colonization or carriage among health-care workers",
abstract = "In Oman, the prevalence of health care associated methicillin resistant Staphylococcus aureus [HA-MRSA] is unknown. Therefore, to estimate the prevalence of HA-MRSA, we collected nasal swabs and swabs from cell phones on sterile polyester swabs and immediately inoculated on the mannitol salt agar containing oxacillin from medical students and hospital health care providers. Antibiotic susceptibility testing of the isolates was then performed using the Kirby Bauer's disc diffusion method. Additionally, a brief survey questionnaire was used to acquire demographic data. Amongst the 311 participants enrolled, nasal colonization with HA-MRSA was found in 47 individuals (15.1{\%}, 95{\%} confidence interval [CI] = 11.1{\%}, 19.1{\%}). HA-MRSA was also isolated from the cell phone surfaces in 28 participants (9.0{\%}, 95{\%} CI = 8.6{\%}, 9.3{\%}). 5 participants (1.6{\%}) showed positive results both from their nasal swabs and from their cell phones. Antibiotic resistance to erythromycin [48{\%}] and clindamycin [29{\%}] was relatively high. 9.3{\%} HA-MRSA isolates were vancomycin resistant [6.6{\%} nasal carriage]. There was no statistically significant correlation between HA-MRSA isolates and the demographic characteristics or the risk factors namely gender, underlying co-morbidities like diabetes, hypertension, skin/soft tissue infections, skin ulcers/wounds, recent exposure to antibiotics, or hospital visits (p >. 0.05, Chi-square test).",
keywords = "HA-MRSA, Methicillin, Nasal, Oxacillin, Prevalence, Staphylococcus aureus",
author = "Pathare, {Nirmal A.} and Harshini Asogan and Sara Tejani and {Al Mahruqi}, Gaitha and {Al Fakhri}, Salma and Roshna Zafarulla and Pathare, {Anil V.}",
year = "2015",
month = "8",
day = "4",
doi = "10.1016/j.jiph.2015.12.004",
language = "English",
journal = "Journal of Infection and Public Health",
issn = "1876-0341",
publisher = "Elsevier BV",

}

TY - JOUR

T1 - Prevalence of methicillin resistant Staphylococcus aureus [MRSA] colonization or carriage among health-care workers

AU - Pathare, Nirmal A.

AU - Asogan, Harshini

AU - Tejani, Sara

AU - Al Mahruqi, Gaitha

AU - Al Fakhri, Salma

AU - Zafarulla, Roshna

AU - Pathare, Anil V.

PY - 2015/8/4

Y1 - 2015/8/4

N2 - In Oman, the prevalence of health care associated methicillin resistant Staphylococcus aureus [HA-MRSA] is unknown. Therefore, to estimate the prevalence of HA-MRSA, we collected nasal swabs and swabs from cell phones on sterile polyester swabs and immediately inoculated on the mannitol salt agar containing oxacillin from medical students and hospital health care providers. Antibiotic susceptibility testing of the isolates was then performed using the Kirby Bauer's disc diffusion method. Additionally, a brief survey questionnaire was used to acquire demographic data. Amongst the 311 participants enrolled, nasal colonization with HA-MRSA was found in 47 individuals (15.1%, 95% confidence interval [CI] = 11.1%, 19.1%). HA-MRSA was also isolated from the cell phone surfaces in 28 participants (9.0%, 95% CI = 8.6%, 9.3%). 5 participants (1.6%) showed positive results both from their nasal swabs and from their cell phones. Antibiotic resistance to erythromycin [48%] and clindamycin [29%] was relatively high. 9.3% HA-MRSA isolates were vancomycin resistant [6.6% nasal carriage]. There was no statistically significant correlation between HA-MRSA isolates and the demographic characteristics or the risk factors namely gender, underlying co-morbidities like diabetes, hypertension, skin/soft tissue infections, skin ulcers/wounds, recent exposure to antibiotics, or hospital visits (p >. 0.05, Chi-square test).

AB - In Oman, the prevalence of health care associated methicillin resistant Staphylococcus aureus [HA-MRSA] is unknown. Therefore, to estimate the prevalence of HA-MRSA, we collected nasal swabs and swabs from cell phones on sterile polyester swabs and immediately inoculated on the mannitol salt agar containing oxacillin from medical students and hospital health care providers. Antibiotic susceptibility testing of the isolates was then performed using the Kirby Bauer's disc diffusion method. Additionally, a brief survey questionnaire was used to acquire demographic data. Amongst the 311 participants enrolled, nasal colonization with HA-MRSA was found in 47 individuals (15.1%, 95% confidence interval [CI] = 11.1%, 19.1%). HA-MRSA was also isolated from the cell phone surfaces in 28 participants (9.0%, 95% CI = 8.6%, 9.3%). 5 participants (1.6%) showed positive results both from their nasal swabs and from their cell phones. Antibiotic resistance to erythromycin [48%] and clindamycin [29%] was relatively high. 9.3% HA-MRSA isolates were vancomycin resistant [6.6% nasal carriage]. There was no statistically significant correlation between HA-MRSA isolates and the demographic characteristics or the risk factors namely gender, underlying co-morbidities like diabetes, hypertension, skin/soft tissue infections, skin ulcers/wounds, recent exposure to antibiotics, or hospital visits (p >. 0.05, Chi-square test).

KW - HA-MRSA

KW - Methicillin

KW - Nasal

KW - Oxacillin

KW - Prevalence

KW - Staphylococcus aureus

UR - http://www.scopus.com/inward/record.url?scp=84952893862&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84952893862&partnerID=8YFLogxK

U2 - 10.1016/j.jiph.2015.12.004

DO - 10.1016/j.jiph.2015.12.004

M3 - Article

JO - Journal of Infection and Public Health

JF - Journal of Infection and Public Health

SN - 1876-0341

ER -