Abstract
Objective: To estimate the prevalence as well as predictors of low high-density lipoprotein cholesterol (HDL-C) levels among acute coronary syndrome (ACS) patients in Oman. Methods: Data were analyzed from the records of 1583 consecutive patients admitted with a diagnosis of ACS as part of the Gulf Registry of Acute Coronary Events (Gulf RACE). A low HDL-C was considered as 2 mg/dL), triglycerides, and body mass index (BMI) were positive predictors of low HDL-C. However, male gender, total cholesterol, and heart failure (Killip class score ≥3) were negative predictors of low HDL-C. Conclusions: Omani ACS patients have a high prevalence of low HDL-C. Renal impairment, triglycerides, and BMI were positive predictors of low HDL-C. The clinical relevance of a low HDL-C abnormality needs to be evaluated in light of the study's limitations (e.g., cross sectional study design as well as the effects of the acute phase reaction and treatment).
| Original language | English |
|---|---|
| Pages (from-to) | 879-885 |
| Number of pages | 7 |
| Journal | Current Medical Research and Opinion |
| Volume | 27 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 2011 |
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Keywords
- Acute coronary syndrome
- High density lipoprotein cholesterol
- Low density lipoprotein cholesterol
- Oman
- Triglycerides
ASJC Scopus subject areas
- Medicine(all)
Cite this
Prevalence of low high-density lipoprotein cholesterol (HDL-C) as a marker of residual cardiovascular risk among acute coronary syndrome patients from Oman. / Al-Zakwani, Ibrahim; Sulaiman, Kadhim; Al-Rasadi, Khalid; Mikhailidis, Dimitri P.
In: Current Medical Research and Opinion, Vol. 27, No. 4, 04.2011, p. 879-885.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence of low high-density lipoprotein cholesterol (HDL-C) as a marker of residual cardiovascular risk among acute coronary syndrome patients from Oman
AU - Al-Zakwani, Ibrahim
AU - Sulaiman, Kadhim
AU - Al-Rasadi, Khalid
AU - Mikhailidis, Dimitri P.
PY - 2011/4
Y1 - 2011/4
N2 - Objective: To estimate the prevalence as well as predictors of low high-density lipoprotein cholesterol (HDL-C) levels among acute coronary syndrome (ACS) patients in Oman. Methods: Data were analyzed from the records of 1583 consecutive patients admitted with a diagnosis of ACS as part of the Gulf Registry of Acute Coronary Events (Gulf RACE). A low HDL-C was considered as 2 mg/dL), triglycerides, and body mass index (BMI) were positive predictors of low HDL-C. However, male gender, total cholesterol, and heart failure (Killip class score ≥3) were negative predictors of low HDL-C. Conclusions: Omani ACS patients have a high prevalence of low HDL-C. Renal impairment, triglycerides, and BMI were positive predictors of low HDL-C. The clinical relevance of a low HDL-C abnormality needs to be evaluated in light of the study's limitations (e.g., cross sectional study design as well as the effects of the acute phase reaction and treatment).
AB - Objective: To estimate the prevalence as well as predictors of low high-density lipoprotein cholesterol (HDL-C) levels among acute coronary syndrome (ACS) patients in Oman. Methods: Data were analyzed from the records of 1583 consecutive patients admitted with a diagnosis of ACS as part of the Gulf Registry of Acute Coronary Events (Gulf RACE). A low HDL-C was considered as 2 mg/dL), triglycerides, and body mass index (BMI) were positive predictors of low HDL-C. However, male gender, total cholesterol, and heart failure (Killip class score ≥3) were negative predictors of low HDL-C. Conclusions: Omani ACS patients have a high prevalence of low HDL-C. Renal impairment, triglycerides, and BMI were positive predictors of low HDL-C. The clinical relevance of a low HDL-C abnormality needs to be evaluated in light of the study's limitations (e.g., cross sectional study design as well as the effects of the acute phase reaction and treatment).
KW - Acute coronary syndrome
KW - High density lipoprotein cholesterol
KW - Low density lipoprotein cholesterol
KW - Oman
KW - Triglycerides
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U2 - 10.1185/03007995.2011.559537
DO - 10.1185/03007995.2011.559537
M3 - Article
VL - 27
SP - 879
EP - 885
JO - Current Medical Research and Opinion
JF - Current Medical Research and Opinion
SN - 0300-7995
IS - 4
ER -