TY - JOUR
T1 - Prevalence of low high-density lipoprotein cholesterol (HDL-C) as a marker of residual cardiovascular risk among acute coronary syndrome patients from Oman
AU - Al-Zakwani, Ibrahim
AU - Sulaiman, Kadhim
AU - Al-Rasadi, Khalid
AU - Mikhailidis, Dimitri P.
PY - 2011/4
Y1 - 2011/4
N2 - Objective: To estimate the prevalence as well as predictors of low high-density lipoprotein cholesterol (HDL-C) levels among acute coronary syndrome (ACS) patients in Oman. Methods: Data were analyzed from the records of 1583 consecutive patients admitted with a diagnosis of ACS as part of the Gulf Registry of Acute Coronary Events (Gulf RACE). A low HDL-C was considered as 2 mg/dL), triglycerides, and body mass index (BMI) were positive predictors of low HDL-C. However, male gender, total cholesterol, and heart failure (Killip class score ≥3) were negative predictors of low HDL-C. Conclusions: Omani ACS patients have a high prevalence of low HDL-C. Renal impairment, triglycerides, and BMI were positive predictors of low HDL-C. The clinical relevance of a low HDL-C abnormality needs to be evaluated in light of the study's limitations (e.g., cross sectional study design as well as the effects of the acute phase reaction and treatment).
AB - Objective: To estimate the prevalence as well as predictors of low high-density lipoprotein cholesterol (HDL-C) levels among acute coronary syndrome (ACS) patients in Oman. Methods: Data were analyzed from the records of 1583 consecutive patients admitted with a diagnosis of ACS as part of the Gulf Registry of Acute Coronary Events (Gulf RACE). A low HDL-C was considered as 2 mg/dL), triglycerides, and body mass index (BMI) were positive predictors of low HDL-C. However, male gender, total cholesterol, and heart failure (Killip class score ≥3) were negative predictors of low HDL-C. Conclusions: Omani ACS patients have a high prevalence of low HDL-C. Renal impairment, triglycerides, and BMI were positive predictors of low HDL-C. The clinical relevance of a low HDL-C abnormality needs to be evaluated in light of the study's limitations (e.g., cross sectional study design as well as the effects of the acute phase reaction and treatment).
KW - Acute coronary syndrome
KW - High density lipoprotein cholesterol
KW - Low density lipoprotein cholesterol
KW - Oman
KW - Triglycerides
UR - http://www.scopus.com/inward/record.url?scp=79952693175&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79952693175&partnerID=8YFLogxK
U2 - 10.1185/03007995.2011.559537
DO - 10.1185/03007995.2011.559537
M3 - Article
C2 - 21332274
AN - SCOPUS:79952693175
VL - 27
SP - 879
EP - 885
JO - Current Medical Research and Opinion
JF - Current Medical Research and Opinion
SN - 0300-7995
IS - 4
ER -