Prevalence of hepatitis C among multi-transfused thalassaemic patients in Oman single centre experience

Khalid Al-Naamani, Ibrahim Al-Zakwani, Siham Al-Sinani, Fauzia Wasim, Shahina Daar

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objectives: Regular blood transfusions are essential for patients with thalassaemia major. However, infections with hepatotropic viruses remain a major concern. The objective of this study was to evaluate the prevalence and characteristics of hepatitis C viral (HCV) infection among patients with homozygous beta thalassaemia in a single centre in Oman. Methods: A retrospective chart review of 200 patients treated at the Thalassemia Unit of Sultan Qaboos University Hospital (SQUH) in Muscat, Oman, between August 1991 and December 2011 was performed. Relevant demographic and clinical characteristics were collected, including age, gender, HCV status and the presence of endocrinopathies. Results: A total of 81 patients (41%) were found to be anti-HCV-antibody (anti-HCV)-positive. HCV ribonucleic acid tests were performed on 65 anti-HCV-positive patients and were positive among 33 (51%); the remaining 16 patients died before these tests were available. Anti-HCV-positive patients were significantly older than anti-HCV-negative patients (P

Original languageEnglish
Pages (from-to)e46-e51
JournalSultan Qaboos University Medical Journal
Volume15
Issue number1
Publication statusPublished - 2015

Keywords

  • Anti-HCV Antibodies
  • Beta Thalassemia
  • Blood Safety
  • Blood Transfusions
  • Hepatitis C
  • Oman
  • Seroprevalence

ASJC Scopus subject areas

  • Medicine(all)

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