Prescribing pattern of antifungal medications at a tertiary care hospital in Oman

Research output: Contribution to journalArticle

Abstract

Introduction: Inappropriate use of antifungal agents is implicated in the global burden of antifungal resistance, adverse outcomes like persistent infections, unnecessary exposure and increased cost. Data collection from time to time is to be done in order to have a check on the resistance/sensitivity pattern of the commonly prescribed antifungal drugs. Aim: To describe the pattern of antifungal drug prescription and administration to patients attending a university hospital in Oman. Materials and Methods: This was a descriptive, retrospective cross-sectional study conducted at Sultan Qaboos University Hospital (SQUH), a university hospital in Oman that covered the electronic patient’s data for a period of one year (January 2013 to December 2013). The study included inpatients and outpatients of all ages and both genders attending SQUH and receiving antifungal medications at the study period. Frequencies and percentages were reported for categorical variables, while the mean and standard deviation were used to summarize the data for continuous variables. Results: A total of 1353 antifungal drug prescriptions were prescribed for 244 patients. More than half of all antifungal drug prescriptions were prescribed by haematology, infectious disease and family medicine departments. The majority of patients to whom these drugs were prescribed were diagnosed to have infectious diseases followed by prophylactic use in leukaemias and immunocompromised conditions. Fluconazole was the most commonly prescribed antifungal drug (n= 715, 52.8%) followed by nystatin and voriconazole (n=233; 17.2% and n= 152; 11.2%, respectively). Conclusion: This study will help in understanding antifungal prescription practices and help in directing future studies and also in developing local policies for appropriate use of antifungal drugs.

Original languageEnglish
Pages (from-to)FC27-FC30
JournalJournal of Clinical and Diagnostic Research
Volume10
Issue number12
DOIs
Publication statusPublished - Dec 1 2016

Fingerprint

Oman
Tertiary Healthcare
Drug Prescriptions
Tertiary Care Centers
Pharmaceutical Preparations
Infectious Disease Medicine
Nystatin
Fluconazole
Antifungal Agents
Hematology
Prescriptions
Communicable Diseases
Inpatients
Leukemia
Outpatients
Cross-Sectional Studies
Costs and Cost Analysis
Medicine
Infection
Sultan

Keywords

  • Amphotericin B
  • Fungal infections
  • Tinea pedis

ASJC Scopus subject areas

  • Medicine(all)
  • Clinical Biochemistry

Cite this

Prescribing pattern of antifungal medications at a tertiary care hospital in Oman. / Al Balushi, Khalid A.; Alzaabi, Mohammed A.; Alghafri, Fatma.

In: Journal of Clinical and Diagnostic Research, Vol. 10, No. 12, 01.12.2016, p. FC27-FC30.

Research output: Contribution to journalArticle

@article{f3c920bf0f6c4793a24b68ae891b3796,
title = "Prescribing pattern of antifungal medications at a tertiary care hospital in Oman",
abstract = "Introduction: Inappropriate use of antifungal agents is implicated in the global burden of antifungal resistance, adverse outcomes like persistent infections, unnecessary exposure and increased cost. Data collection from time to time is to be done in order to have a check on the resistance/sensitivity pattern of the commonly prescribed antifungal drugs. Aim: To describe the pattern of antifungal drug prescription and administration to patients attending a university hospital in Oman. Materials and Methods: This was a descriptive, retrospective cross-sectional study conducted at Sultan Qaboos University Hospital (SQUH), a university hospital in Oman that covered the electronic patient’s data for a period of one year (January 2013 to December 2013). The study included inpatients and outpatients of all ages and both genders attending SQUH and receiving antifungal medications at the study period. Frequencies and percentages were reported for categorical variables, while the mean and standard deviation were used to summarize the data for continuous variables. Results: A total of 1353 antifungal drug prescriptions were prescribed for 244 patients. More than half of all antifungal drug prescriptions were prescribed by haematology, infectious disease and family medicine departments. The majority of patients to whom these drugs were prescribed were diagnosed to have infectious diseases followed by prophylactic use in leukaemias and immunocompromised conditions. Fluconazole was the most commonly prescribed antifungal drug (n= 715, 52.8{\%}) followed by nystatin and voriconazole (n=233; 17.2{\%} and n= 152; 11.2{\%}, respectively). Conclusion: This study will help in understanding antifungal prescription practices and help in directing future studies and also in developing local policies for appropriate use of antifungal drugs.",
keywords = "Amphotericin B, Fungal infections, Tinea pedis",
author = "{Al Balushi}, {Khalid A.} and Alzaabi, {Mohammed A.} and Fatma Alghafri",
year = "2016",
month = "12",
day = "1",
doi = "10.7860/JCDR/2016/23591.9005",
language = "English",
volume = "10",
pages = "FC27--FC30",
journal = "Journal of Clinical and Diagnostic Research",
issn = "2249-782X",
publisher = "JCDR Research and Publications (Pvt) Limited",
number = "12",

}

TY - JOUR

T1 - Prescribing pattern of antifungal medications at a tertiary care hospital in Oman

AU - Al Balushi, Khalid A.

AU - Alzaabi, Mohammed A.

AU - Alghafri, Fatma

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Introduction: Inappropriate use of antifungal agents is implicated in the global burden of antifungal resistance, adverse outcomes like persistent infections, unnecessary exposure and increased cost. Data collection from time to time is to be done in order to have a check on the resistance/sensitivity pattern of the commonly prescribed antifungal drugs. Aim: To describe the pattern of antifungal drug prescription and administration to patients attending a university hospital in Oman. Materials and Methods: This was a descriptive, retrospective cross-sectional study conducted at Sultan Qaboos University Hospital (SQUH), a university hospital in Oman that covered the electronic patient’s data for a period of one year (January 2013 to December 2013). The study included inpatients and outpatients of all ages and both genders attending SQUH and receiving antifungal medications at the study period. Frequencies and percentages were reported for categorical variables, while the mean and standard deviation were used to summarize the data for continuous variables. Results: A total of 1353 antifungal drug prescriptions were prescribed for 244 patients. More than half of all antifungal drug prescriptions were prescribed by haematology, infectious disease and family medicine departments. The majority of patients to whom these drugs were prescribed were diagnosed to have infectious diseases followed by prophylactic use in leukaemias and immunocompromised conditions. Fluconazole was the most commonly prescribed antifungal drug (n= 715, 52.8%) followed by nystatin and voriconazole (n=233; 17.2% and n= 152; 11.2%, respectively). Conclusion: This study will help in understanding antifungal prescription practices and help in directing future studies and also in developing local policies for appropriate use of antifungal drugs.

AB - Introduction: Inappropriate use of antifungal agents is implicated in the global burden of antifungal resistance, adverse outcomes like persistent infections, unnecessary exposure and increased cost. Data collection from time to time is to be done in order to have a check on the resistance/sensitivity pattern of the commonly prescribed antifungal drugs. Aim: To describe the pattern of antifungal drug prescription and administration to patients attending a university hospital in Oman. Materials and Methods: This was a descriptive, retrospective cross-sectional study conducted at Sultan Qaboos University Hospital (SQUH), a university hospital in Oman that covered the electronic patient’s data for a period of one year (January 2013 to December 2013). The study included inpatients and outpatients of all ages and both genders attending SQUH and receiving antifungal medications at the study period. Frequencies and percentages were reported for categorical variables, while the mean and standard deviation were used to summarize the data for continuous variables. Results: A total of 1353 antifungal drug prescriptions were prescribed for 244 patients. More than half of all antifungal drug prescriptions were prescribed by haematology, infectious disease and family medicine departments. The majority of patients to whom these drugs were prescribed were diagnosed to have infectious diseases followed by prophylactic use in leukaemias and immunocompromised conditions. Fluconazole was the most commonly prescribed antifungal drug (n= 715, 52.8%) followed by nystatin and voriconazole (n=233; 17.2% and n= 152; 11.2%, respectively). Conclusion: This study will help in understanding antifungal prescription practices and help in directing future studies and also in developing local policies for appropriate use of antifungal drugs.

KW - Amphotericin B

KW - Fungal infections

KW - Tinea pedis

UR - http://www.scopus.com/inward/record.url?scp=85000797844&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85000797844&partnerID=8YFLogxK

U2 - 10.7860/JCDR/2016/23591.9005

DO - 10.7860/JCDR/2016/23591.9005

M3 - Article

AN - SCOPUS:85000797844

VL - 10

SP - FC27-FC30

JO - Journal of Clinical and Diagnostic Research

JF - Journal of Clinical and Diagnostic Research

SN - 2249-782X

IS - 12

ER -