TY - JOUR
T1 - Prepubertal hypertransfusion in talassemia intermedia
T2 - A case report of sustained positive efects on growth, splenic function and endocrine parameters
AU - Tony, Surekha
AU - Daar, Shahina
AU - Zachariah, Mathew
AU - Wali, Yasser
PY - 2012
Y1 - 2012
N2 - We report a known case of thalassemia intermedia (Hb Dhofar) who in spite of mild thalassemic facies, attained his normal genetic height, pubertal maturity and improved self-image with minimal splenomegaly through a hypertransfusion/chelation regimen that was started just before puberty and maintained for 5 years. As there are no clear guidelines in the management of patients with thalassemia intermedia, the option of hypertransfusion/ chelation during the pubertal growth spurt may alleviate some of the complications associated with thalassemia intermedia.
AB - We report a known case of thalassemia intermedia (Hb Dhofar) who in spite of mild thalassemic facies, attained his normal genetic height, pubertal maturity and improved self-image with minimal splenomegaly through a hypertransfusion/chelation regimen that was started just before puberty and maintained for 5 years. As there are no clear guidelines in the management of patients with thalassemia intermedia, the option of hypertransfusion/ chelation during the pubertal growth spurt may alleviate some of the complications associated with thalassemia intermedia.
KW - Hypertransfusion
KW - Prepuberty
KW - Talassemia intermedia
UR - http://www.scopus.com/inward/record.url?scp=84873293675&partnerID=8YFLogxK
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U2 - 10.5001/omj.2012.125
DO - 10.5001/omj.2012.125
M3 - Article
AN - SCOPUS:84873293675
SN - 1999-768X
VL - 27
JO - Oman Medical Journal
JF - Oman Medical Journal
IS - 6
ER -