Keeping in view the interesting chemistry and pharmacological importance of harmine series of bases - the β-carboline alkaloids, a number of new derivatives of tetrahydroharmine (1) and harmalol (2) have been prepared and characterized through spectral studies. Some of these derivatives showed spasmolytic activity. It was observed that all the N -acyl tetrahydroharmine derivatives are stable, not labile and no ring opening occurs in these compounds, as reported recently.
|Number of pages||15|
|Journal||Natural Product Research|
|Publication status||Published - Mar 2006|
ASJC Scopus subject areas
- Analytical Chemistry
- Plant Science
- Organic Chemistry