Predictive Value of Neutrophil to Lymphocyte Ratio in Outcomes of Patients with Acute Coronary Syndrome

M. A R Muhmmed Suliman, Abdullah Abdulaziz Bahnacy Juma, Ali Ahmed Ali Almadhani, Anil Vasant Pathare, S. S A Alkindi, Fass Uwe Werner

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Background and Aims: Acute coronary syndrome (ACS) is associated with many hereditary and acquired predisposing factors. It has been recently shown that inflammation may play a role in myocardial ischemia. Hence, the white blood cell (WBC) count provides a simple and inexpensive method for assessment of inflammatory status in patients with ACS. An elevated WBC count has been associated with cardiovascular risk, but which leukocyte subtype carries this risk is uncertain. The aim of this study was to investigate the utility of admission neutrophil/lymphocyte ratio (NLR) in predicting the likelihood of poor outcomes in patients with ACS. Methods: A total of 300 consecutive patients admitted to the Internal Medicine Department, Sohar Hospital, Oman with the diagnosis of ACS from June 2008 to May 2009 were included in this study. Patients were divided into tertile groups according to the NLR. The primary end point was all-cause in-hospital mortality at the end of 30 days. Results: The mean age of patients included in this cohort was 61 years, with 63% of male patients. The mortality in the three groups based on NLR was 4, 10 and 19%, in the low-, middle- and high-risk groups, respectively (p 2 test). Conclusions: Admission NLR is clearly an independent predictor of all-cause mortality in patients with ACS.

Original languageEnglish
Pages (from-to)618-622
Number of pages5
JournalArchives of Medical Research
Volume41
Issue number8
DOIs
Publication statusPublished - Nov 2010

Fingerprint

Acute Coronary Syndrome
Neutrophils
Lymphocytes
Leukocyte Count
Oman
Mortality
Hospital Departments
Internal Medicine
Hospital Mortality
Causality
Myocardial Ischemia
Leukocytes
Inflammation

Keywords

  • Acute coronary syndrome
  • Inflammation
  • Ischemia
  • Neutrophil/lymphocyte ratio

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Predictive Value of Neutrophil to Lymphocyte Ratio in Outcomes of Patients with Acute Coronary Syndrome. / Muhmmed Suliman, M. A R; Bahnacy Juma, Abdullah Abdulaziz; Ali Almadhani, Ali Ahmed; Pathare, Anil Vasant; Alkindi, S. S A; Uwe Werner, Fass.

In: Archives of Medical Research, Vol. 41, No. 8, 11.2010, p. 618-622.

Research output: Contribution to journalArticle

Muhmmed Suliman, M. A R ; Bahnacy Juma, Abdullah Abdulaziz ; Ali Almadhani, Ali Ahmed ; Pathare, Anil Vasant ; Alkindi, S. S A ; Uwe Werner, Fass. / Predictive Value of Neutrophil to Lymphocyte Ratio in Outcomes of Patients with Acute Coronary Syndrome. In: Archives of Medical Research. 2010 ; Vol. 41, No. 8. pp. 618-622.
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