TY - JOUR
T1 - Posterior reversible encephalopathy syndrome in two Omani children with underlying renal diseases
AU - El-Naggari, Mohamed A.
AU - Al-Nabhani, Dana
AU - El-Nour, Ibtisam
AU - El-Manzalawy, Alaa
AU - Abdelmogheth, Anas Alwogud A.
N1 - Publisher Copyright:
© 2015, Sultan Qaboos University. All rights reserved.
PY - 2015
Y1 - 2015
N2 - Posterior reversible encephalopathy syndrome (PRES) is a neurological condition with a combination of clinical and radiological features. Clinical symptoms include headaches, confusion, seizures, disturbed vision or an altered level of consciousness. Classic magnetic resonance imaging (MRI) findings indicate subcortical and cortical oedema, affecting mainly the posterior cerebral region. We report two paediatric cases of PRES with underlying renal diseases presenting at the Sultan Qaboos University Hospital in Muscat, Oman, in April 2010 and August 2011. The first case was an 11-year-old girl diagnosed with systemic lupus erythematosus and the second was a six-and-a-half-year-old boy on peritoneal dialysis due to multi-drug-resistant nephrotic syndrome. Both patients were hypertensive and treated with blood pressure control medications. No residual neurological dysfunction was noted in the patients at a one-year follow-up and at discharge, respectively. The role of hypertension in paediatric PRES cases, among other important risk factors, is emphasised. Additionally, MRI is an important diagnostic and prognostic tool. Prompt diagnosis and aggressive management is fundamental to preventing permanent neurological damage.
AB - Posterior reversible encephalopathy syndrome (PRES) is a neurological condition with a combination of clinical and radiological features. Clinical symptoms include headaches, confusion, seizures, disturbed vision or an altered level of consciousness. Classic magnetic resonance imaging (MRI) findings indicate subcortical and cortical oedema, affecting mainly the posterior cerebral region. We report two paediatric cases of PRES with underlying renal diseases presenting at the Sultan Qaboos University Hospital in Muscat, Oman, in April 2010 and August 2011. The first case was an 11-year-old girl diagnosed with systemic lupus erythematosus and the second was a six-and-a-half-year-old boy on peritoneal dialysis due to multi-drug-resistant nephrotic syndrome. Both patients were hypertensive and treated with blood pressure control medications. No residual neurological dysfunction was noted in the patients at a one-year follow-up and at discharge, respectively. The role of hypertension in paediatric PRES cases, among other important risk factors, is emphasised. Additionally, MRI is an important diagnostic and prognostic tool. Prompt diagnosis and aggressive management is fundamental to preventing permanent neurological damage.
KW - Case report
KW - Magnetic resonance imaging
KW - Oman
KW - Pediatrics
KW - Peritoneal dialysis
KW - Posterior reversible encephalopathy syndrome
KW - Systemic lupus erythematosus
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U2 - 10.18295/squmj.2015.15.03.020
DO - 10.18295/squmj.2015.15.03.020
M3 - Article
C2 - 26357562
AN - SCOPUS:84940037050
SN - 2075-051X
VL - 15
SP - e424-e428
JO - Sultan Qaboos University Medical Journal
JF - Sultan Qaboos University Medical Journal
IS - 3
ER -